Subscribe to RSS

DOI: 10.1055/s-0045-1810620
Malnutrition among Pediatric Cancer Patients: A Study of Government Hospitals in Delhi
Funding None.

Abstract
Introduction
Research indicates a considerably higher incidence of malnutrition at the time of diagnosis among patients with pediatric cancer. Studies have also shown that malnutrition tends to worsen with anti-cancer therapies. However, there are limited studies conducted in the Indian context, and those available often involve small sample sizes.
Objectives
This study aims to address this gap by analyzing data of patients with pediatric cancer treated at two government hospitals in Delhi.
Materials and Methods
This retrospective study includes data from 1,042 patients with pediatric cancer, collected over 6 years from April 2018 to April 2024. The dataset includes age at diagnosis, cancer type, and anthropometric measurements recorded at the initial contact. The analysis focuses on the prevalence of malnutrition, stratified by gender, age group, and cancer type.
Results
Among patients with pediatric cancer, more than 80% were diagnosed with hematological malignancies. This study identified an overall malnutrition prevalence of 39.7% (414 out of 1,042). Notably, the prevalence increases with age.
Conclusion
Given the substantially higher levels of malnutrition among patients with pediatric cancer at baseline and the anticipated increase during anticancer therapy, there is a pressing need for close monitoring and the development of targeted, individualized nutritional interventions. Such measures are essential to mitigate the impact of malnutrition on treatment outcomes and quality of life.
Keywords
malnutrition - incidence - pediatric cancer - WHO norms - acute lymphoblastic leukemia - prevalenceAuthors' Contributions
A.S.—Concept design, definition of intellectual content, clinical studies, data acquisition, manuscript preparation, manuscript editing, and manuscript review.
P.M.—Concept design, definition of intellectual content, manuscript preparation, manuscript editing, and manuscript review.
P.B.—Concept design, definition of intellectual content, manuscript preparation, manuscript editing, and manuscript review.
N.F.—Concept design, definition of intellectual content, literature search, data acquisition, manuscript preparation, manuscript editing, and manuscript review.
K.S.—Concept design, definition of intellectual content, literature search, clinical studies, experimental studies, data acquisition, data analysis, manuscript preparation, manuscript editing, and manuscript review.
H.G.—Concept design, definition of intellectual content, manuscript preparation, manuscript editing, and manuscript review.
P. Sharma—Concept, design, definition of intellectual content, literature search, manuscript preparation, manuscript editing, and manuscript review.
P. Singh—Concept, design, definition of intellectual content, literature search, data analysis, statistical analysis, manuscript preparation, manuscript editing, and manuscript review.
A.K.—Concept, design, definition of intellectual content, literature search, manuscript preparation, manuscript editing, and manuscript review.
The manuscript has been read and approved by all the authors that the requirements for authorship have been met and that each author believes that the manuscript represents honest work.
Patient's Consent
Patient consent is not required due to the retrospective nature of the study.
Publication History
Article published online:
18 August 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Gupta H, Pant G, Verma N. Malnutrition in childhood cancer patients: Magnitude, key indicators and outcome. Pediatric Hematology Oncology Journal 2022; 7 (04) 155-160
- 2 Jain V, Dubey AP, Gupta SK. Nutritional parameters in children with malignancy. Indian Pediatr 2003; 40 (10) 976-984
- 3 Sakthikumar L, Sneha LM, Chandran S, Scott J, Soundarapandiyan L, Kumar Y. Clinical implications of undernutrition in childhood cancer: a single centre experience from a developing country. Int J Nutr Pharmacol Neurol Dis 2021; 11 (02) 163
- 4 Radhakrishnan V, Ganesan P, Rajendranath R, Ganesan TS, Sagar TG. Nutritional profile of pediatric cancer patients at Cancer Institute, Chennai. Indian J Cancer 2015; 52 (02) 207-209
- 5 World Health Organization. The WHO Child Growth Standards. www.who.int. Published 2009. Accessed July 23, 2025 at: https://www.who.int/tools/child-growth-standards/standards
- 6 World Health Organization (WHO) classification of nutritional status of infants and children. Published 2017 . Accessed July 23, 2025 at: https://www.ncbi.nlm.nih.gov/books/NBK487900/table/fm.s1.t1/
- 7 Kumar R, Author L, Kinjawadekar U, Ali M. . Indian Academy of Pediatrics (IAP) under the Auspices of the IAP Action Plan 2022 Upendra Kinjawadekar Severe Acute Malnutrition. Accessed July 23, 2025 at: https://iapindia.org/pdf/Ch-136-Severe-Acute-Malnutrition.pdf
- 8 Ward E, DeSantis C, Robbins A, Kohler B, Jemal A. Childhood and adolescent cancer statistics, 2014. CA Cancer J Clin 2014; 64 (02) 83-103
- 9 Diakatou V, Vassilakou T. Nutritional status of pediatric cancer patients at diagnosis and correlations with treatment, clinical outcome and the long-term growth and health of survivors. Children (Basel) 2020; 7 (11) 218
- 10 Maia-Lemos PS, Ceragioli Oliveira FL, Monteiro-Caran EM. Nutritional status at diagnosis in children with cancer in Brazil. Pediatr Ther 2016; 6 (03)
- 11 Brinksma A, Huizinga G, Sulkers E, Kamps W, Roodbol P, Tissing W. Malnutrition in childhood cancer patients: a review on its prevalence and possible causes. Crit Rev Oncol Hematol 2012; 83 (02) 249-275
- 12 Lemos Pdos SM, de Oliveira FLC, Caran EMM. Nutritional status of children and adolescents at diagnosis of hematological and solid malignancies. Rev Bras Hematol Hemoter 2014; 36 (06) 420-423
- 13 Huibers MHW, Manda G, Silverstein A. et al. The burden of malnutrition in childhood cancer in Malawi - risk regardless of age. Nutr Cancer 2022; 74 (09) 3322-3328
- 14 Zimmermann K, Ammann RA, Kuehni CE, De Geest S, Cignacco E. Malnutrition in pediatric patients with cancer at diagnosis and throughout therapy: a multicenter cohort study. Pediatr Blood Cancer 2013; 60 (04) 642-649
- 15 Barr RD. Nutritional status in children with cancer: before, during and after therapy. Indian J Cancer 2015; 52 (02) 173-175
- 16 Peccatori N, Ortiz R, Rossi E. et al. Oral/enteral nutritional supplementation in children treated for cancer in low-middle-income countries is feasible and effective: the experience of the Children's Hospital Manuel de Jesus Rivera “La Mascota” in Nicaragua. Mediterr J Hematol Infect Dis 2018; 10 (01) e2018038
- 17 Schoeman J. Nutritional assessment and intervention in a pediatric oncology unit. Indian J Cancer 2015; 52 (02) 186-190
- 18 Pedretti L, Massa S, Leardini D. et al. Role of nutrition in pediatric patients with cancer. Nutrients 2023; 15 (03) 710
- 19 Bauer J, Jürgens H, Frühwald MC. Important aspects of nutrition in children with cancer. Adv Nutr 2011; 2 (02) 67-77
- 20 Fabozzi F, Trovato CM, Diamanti A. et al. Management of nutritional needs in pediatric oncology: a consensus statement. Cancers (Basel) 2022; 14 (14) 3378