Abstract
Secondary malignancy can arise in patients with non-Hodgkin's lymphoma (NHL) on long
follow-up. The risk of developing secondary malignancies is increased in NHL survivors,
as compared to normal population and varies according to age, gender, and treatment
modality. The nature of solid organ malignancy in order of frequency includes lung
cancer followed by prostate, bladder, colon, breast, etc. Gynecological malignancy
occurring in an NHL survivor is an extremely rare phenomenon with a low observed/expected
ratio (0.89–0.93) as compared to other solid tumors. We hereby report a case of endocervical
adenocarcinoma arising in a 51-year-old female patient who was a known treated case
of NHL. This case highlights the fact that chemotherapy-induced atypia may mimic malignancy
as well as the rare occurrence of gynecological cancers as a secondary malignancy
in patients with NHL.
Keywords
secondary malignancy - NHL - endocervical adenocarcinoma - gynecological malignancy
- case report
