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CC BY 4.0 · World J Nucl Med
DOI: 10.1055/s-0045-1809951
Case Report

Disseminated Mucormycosis in an Immunocompromised Patient with Richter Transformation of Chronic Lymphocytic Leukemia: A Case Report of Concurrent Findings on [18F]-Fluorodeoxyglucose PET-CT

Abhishek Palsapure
1   Department of Nuclear Medicine, Gujarat Cancer & Research Institute, Ahmedabad, Gujarat, India
,
Ritesh R. Suthar 
1   Department of Nuclear Medicine, Gujarat Cancer & Research Institute, Ahmedabad, Gujarat, India
,
Saloni Rajkotia
1   Department of Nuclear Medicine, Gujarat Cancer & Research Institute, Ahmedabad, Gujarat, India
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Abstract

A case of chronic lymphocytic leukemia/small lymphocytic lymphoma with Richter transformation. After initiating R-CHOP chemotherapy, patient developed severe neutropenia and necrotizing cellulitis, necessitating an above-knee amputation. Subsequent positron emission tomography-computed tomography (PET-CT) imaging revealed new lesions suggestive of an abscess, confirmed as mucormycosis upon biopsy. This report highlights the importance of fludeoxyglucose PET-CT in detecting fungal infections in immunocompromised patients and its role in disease management.

Keywords

FDG PET/CT - infection - lymphoma - mucormycosis - Richter transformation


Publication History

Article published online:
08 July 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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