Open Access
CC BY 4.0 · World J Nucl Med
DOI: 10.1055/s-0045-1809951
Case Report

Disseminated Mucormycosis in an Immunocompromised Patient with Richter Transformation of Chronic Lymphocytic Leukemia: A Case Report of Concurrent Findings on [18F]-Fluorodeoxyglucose PET-CT

Abhishek Palsapure
1   Department of Nuclear Medicine, Gujarat Cancer & Research Institute, Ahmedabad, Gujarat, India
,
1   Department of Nuclear Medicine, Gujarat Cancer & Research Institute, Ahmedabad, Gujarat, India
,
Saloni Rajkotia
1   Department of Nuclear Medicine, Gujarat Cancer & Research Institute, Ahmedabad, Gujarat, India
› Author Affiliations
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Abstract

A case of chronic lymphocytic leukemia/small lymphocytic lymphoma with Richter transformation. After initiating R-CHOP chemotherapy, patient developed severe neutropenia and necrotizing cellulitis, necessitating an above-knee amputation. Subsequent positron emission tomography-computed tomography (PET-CT) imaging revealed new lesions suggestive of an abscess, confirmed as mucormycosis upon biopsy. This report highlights the importance of fludeoxyglucose PET-CT in detecting fungal infections in immunocompromised patients and its role in disease management.



Publication History

Article published online:
08 July 2025

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