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DOI: 10.1055/s-0045-1809634
Open Thoracic Anterolateral Cordotomy – Is There Still Room?
Cordotomia anterolateral torácica aberta – Ainda há espaço?Funding The authors have no personal, financial, or institutional interest in any of the drugs, materials, or devices described in this article.

Abstract
Introduction
Cancer pain encompasses multiple mechanisms, thus falling under the classification of mixed pain. Cordotomy for oncologic pain has been performed since a long time ago, as an open surgical technique or a percutaneous approach.
Objective
We describe here the successful application of an open thoracic cordotomy to treat a young patient with advanced cervical cancer. Additionally, a scoping review was conducted, focusing on the efficacy of open cordotomy for the treatment of cancer pain.
Methods
Following PRISMA guidelines, Medline and Embase were searched for articles reporting open cordotomy to treat mainly oncologic pain. Event rates related to pain and adverse events were recorded and amalgamated between studies. Studies written in English, Portuguese, or Spanish, and published between 1960 and 2023 were included.
Results
Of 495 abstracts retrieved, 22 articles were selected for full-text review, of which 10 manuscripts ultimately met inclusion criteria and were pooled for review. A total of 305 patients treated with an open cordotomy were reported in 10 articles, a complete or partial relief of the pain was present in 90% of the patients and only 10% showed a bad pain response after the procedure. Urinary incontinence, motor weakness, and death have been reported in 13%, 7,5%, and 3% of the studies, respectively.
Conclusions
Pain improvement was observed in patients who underwent open cordotomy with an acceptable risk of complications. However, prospective studies in the area are needed to confirm efficacy. Furthermore, new technologies should be explored for tailoring open cordotomy.
Resumo
Introdução
A dor do câncer envolve múltiplos mecanismos, caindo assim na classificação de dor mista. A cordotomia para dor oncológica é realizada há muito tempo, como uma técnica cirúrgica aberta ou uma abordagem percutânea.
Objetivo
Descrevemos aqui a aplicação bem-sucedida de uma cordotomia torácica aberta para tratar um paciente jovem com câncer cervical avançado. Além disso, uma revisão de escopo foi conduzida, com foco na eficácia da cordotomia aberta para o tratamento da dor do câncer.
Métodos
Seguindo as diretrizes PRISMA, foram pesquisados artigos no Medline e Embase que relataram cordotomia aberta para tratar principalmente dor oncológica. As taxas de eventos relacionados à dor e eventos adversos foram registradas e agrupadas entre os estudos. Foram incluídos estudos escritos em inglês, português ou espanhol e publicados entre 1960 e 2023.
Resultados
Dos 495 resumos recuperados, 22 artigos foram selecionados para revisão de texto completo, dos quais 10 manuscritos preencheram os critérios de inclusão e foram agrupados para revisão. Um total de 305 pacientes tratados com cordotomia aberta foram relatados em 10 artigos, um alívio completo ou parcial da dor esteve presente em 90% e apenas 10% apresentaram uma resposta dolorosa ruim após o procedimento. Incontinência urinária, distúrbios do movimento e morte foram relatadas em 13%, 7,5% e 3% dos estudos, respectivamente.
Conclusões
Foi observada melhora da dor com complicações aceitáveis nos pacientes submetidos à cordotomia aberta. No entanto, estudos prospectivos na área são necessários para confirmar a eficácia. Além disso, novas tecnologias devem ser exploradas para adaptar e refinar a cordotomia aberta.
Author's Contribution
Ângelo Marcel Santana Duarte Araujo, Carlos Alberto Miranda Lyra, and Jorge Dornellys da Silva Lapa conceived and designed the study. Jorge Dornellys da Silva Lapa conducted patient examinations and collected clinical data. Ângelo Marcel Santana Duarte Araujo, Carlos Alberto Miranda Lyra, and Jorge Dornellys da Silva Lapa drafted the manuscript. Arthur Maynart Pereira Oliveira, Pedro Henrique Martins da Cunha, Ricardo Ferrareto Iglesio, Daniel Ciampi de Andrade, and Jorge Dornellys da Silva Lapa revised the manuscript for critically important intellectual content.
Publication History
Received: 02 July 2024
Accepted: 20 March 2025
Article published online:
16 July 2025
© 2025. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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