Factors Influencing the Efficacy of Chinese Medicinals

Abstract

This paper thoroughly explores the multifaceted factors influencing the efficacy of Chinese medicinals and categorizes them into three main groups: medicinal related factors, patient related factors, and practitioner related factors. Regarding medicinal related factors, the place of origin, growing environment, harvesting time, storage conditions, quality control, dosage form selection, compatibility of medicinals, precise dosing, decoction methods, and administration routes all significantly impact efficacy. The place of origin determines the authenticity of medicinals, the growing environment affects their composition, harvesting time influences potency, improper storage leads to deterioration, quality control forms the foundation of efficacy, dosage forms and compatibility of medicinals affect absorption, dosing and decoction methods require precision, and administration routes should be tailored to individuals. Patient related factors include psychological state, individual differences, background, and disease condition. Psychological state affects treatment compliance, individual differences determine medicine responses, background influences patients' understanding of Chinese medicinals, and disease condition directly reflects efficacy. Practitioner related factors encompass theoretical knowledge, clinical experience, inherited practices, psychological state, and professional ethics. Theoretical knowledge guides medication use, clinical experience enhances efficacy, inherited practices influence prescribing styles, psychological state affects doctor–patient communication, and professional ethics ensure medical quality. These interrelated factors collectively influence the efficacy of Chinese medicinals, emphasizing the need for comprehensive consideration in clinical applications to achieve optimal therapeutic outcomes.

Keywords

Chinese medicinals - efficacy of Chinese medicinals - influencing factors - medicinal related factors - patient related factors - practitioner related factors - authentic medicinal materials

CRediT Authorship Contribution Statement

Qichao Liang: Conceptualization, and writing -original draft. Yun Jiang: Formal analysis, and writing-review & editing. Liguo Liang: Investigation, and writing-review & editing. Hualong Liang: Validation, methodology,and writing-review & editing.

Publikationsverlauf

Eingereicht: 12. Januar 2025

Angenommen: 15. März 2025

Artikel online veröffentlicht:
27. Juni 2025

• References

• 1 Li DL, Li Q, Zhao HX. et al. A brief discussion on Zhang Zhongjing's prescriptions: “improvement after one dose, cure after two or three”. Henan Tradit Chin Med 2018; 38 (11) 1625-1626
• 2 Li F. Extensive Records of the Taiping Era. Shenyang: Liaoning Fine Arts Publishing House; 2019
• 3 Zhang ZJ. Treatise on Cold Damage. Beijing: People's Medical Publishing House; 2005
• 4 Zhang ZJ. Synopsis of the Golden Chamber. Beijing: People's Medical Publishing House; 2005
• 5 Zhang LS, Jiang F, Jin XY. et al. Analysis of TCM decoction administration methods based on literature. Glob Tradit Chin Med 2018; 11 (12) 1946-1949
• 6 Li ZH. Discussion on the importance of proper administration of TCM decoctions based on medical cases. Clin J Chin Med 2017; 9 (09) 123-124
• 7 Li J. A brief discussion on Bian Que's “six incurable condition”. Forum Tradit Chin Med 2008; (05) 48
• 8 Nanjing University of Chinese Medicine. Huangdi's Inner Canon of Medicine. Shanghai: Shanghai Scientific & Technical Publishers; 2018
• 9 Wang YF. Exploration of a “knowledge-practice-ability” integrated educational model for graduate students in basic TCM. Chin Med Mod Dist Educ Chin 2020; 18 (18) 46-49
• 10 Traditional Chinese Medicine in China White Paper (Full Text). China J Tradit Chin Med 2016 12. :07(004)
• 11 Wang ZG, Ju FN, Lyu JW. et al. Current status, trends, and reflections on research of TCM academic schools. J Nanjing Univ Chin Med 2022; 23 (06) 351-360