Abstract
Acute myeloid leukemia (AML) accounts for around 15 to 20% of childhood leukemia.
Acute leukemia has variable presenting features and extramedullary manifestations
typically occur in 10 to 20% of patients with AML, even before bone marrow involvement.
Therefore, leukemia may get unnoticed if symptoms from other organs predominate. Acute
pancreatitis, as an initial manifestation of acute leukemia, is seen commonly during
and after the course of chemotherapy.
Here, we report the case of a 16-year-old female patient who presented with pain abdomen,
multiple swellings in the neck, axilla, and breast for 2 months and had jaundice at
presentation was diagnosed to be having acute pancreatitis with AML. Pancreatitis
was resolved after starting cytoreductive chemotherapy. Hence, the causation of pancreatitis
in the index case was likely due to pancreatic infiltration by the leukemic cells,
unlike the common etiologies such as hypercalcemia and chemotherapy drugs seen in
the setting of leukemia.
Keywords
acute myeloid leukemia - acute pancreatitis - case report - extramedullary
