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DOI: 10.1055/s-0045-1809329
A Comprehensive Case Report of Metastatic Intracranial Melanoma with Brief Review of Literature
Funding None.
Abstract
Primary intracranial melanomas are an extremely rare entity and are a diagnosis of exclusion. Malignant melanoma represents the third most common site for cerebral metastasis. We hereby narrate a comprehensive and detailed case of metastatic intracranial melanomas with BRAF mutation, which later on had an extensive systemic spread. The imaging differentials include metastasis, intracranial hemorrhage, or granuloma. The final and definitive diagnosis was attained by detailed clinical, histological, and immunohistochemical evaluation as metastatic malignant pigmented tumor consistent with intracranial melanoma.
Note
All legal entities of this case report will be entitled to Dharamshila Narayana Superspeciality Hospital, New Delhi 110092.
Patients' Consent
All participants provided written informed consent for their participation in the study.
Publication History
Article published online:
04 June 2025
© 2025. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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References
- 1 Chiarion-Sileni V, Murr R, Pigozzo J, Sarti S, Tomassi O, Romanini A. Brain metastases from malignant melanoma. Forum (Genova) 2003; 13 (02) 170-182 , quiz 190
- 2 Spagnolo F, Picasso V, Lambertini M, Ottaviano V, Dozin B, Queirolo P. Survival of patients with metastatic melanoma and brain metastases in the era of MAP-kinase inhibitors and immunologic checkpoint blockade antibodies: a systematic review. Cancer Treat Rev 2016; 45: 38-45
- 3 Davies MA, Liu P, McIntyre S. et al. Prognostic factors for survival in melanoma patients with brain metastases. Cancer 2011; 117 (08) 1687-1696
- 4 Terao H, Yoshimatsu N, Sano K. [Intracranial melanoma]. No To Shinkei 1968; 20 (10) 991-999