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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2026; 36(02): 247-249
DOI: 10.1055/s-0045-1809305
Technical Note

Sclerotic Bone Lesion: A Novel Modification in Biopsy Technique to Increase Diagnostic Yield

Authors

  • Sonal Saran 

    1   Department of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, Uttarakhand, India

  • Simran Suri

    2   SGT Medical College, Hospital, and Research Institute, Gurugram, Haryana, India

  • Nishith Kumar

    3   Department of Radiodiagnosis and Interventional Radiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India

  • Divesh Jalan

    4   Central Institute of Orthopaedics, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India

  • Geetika Khanna

    5   Department of Pathology, Vardhman Mahavir Medical College and Safdarjung, Hospital, New Delhi, India

  • Neha Nischal 

    6   Department of Radiodiagnosis, Holy Family Hospital, New Delhi, India

  • Dharmendra Kumar Singh 

    3   Department of Radiodiagnosis and Interventional Radiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India
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Abstract

Sclerotic bone lesions pose a significant diagnostic challenge due to their low diagnostic yield in core needle biopsy. In this technical note, we propose a novel modification to the standard biopsy technique aimed at improving the diagnostic yield of biopsies performed on sclerotic bone lesions. The modification involves use of trephine needle to acquire one bony core sample then using trucut biopsy needle to acquire samples through the tunnel created by the trephine needle. Our approach leverages optimized instrumentation to increase the likelihood of obtaining sufficient and representative tissue samples from challenging sclerotic lesions. Through a detailed description of the technique and its application in clinical practice, we demonstrate how this modification can significantly improve the diagnostic approach for sclerotic bone lesions, providing clinicians with a reliable method for accurate histopathological diagnosis.

Keywords

sclerotic bone lesion - bone biopsy - C-arm-guided bone biopsy


Publication History

Article published online:
17 May 2025

© 2025. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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