CC BY-NC-ND 4.0 · Revista Chilena de Ortopedia y Traumatología 2025; 66(01): e37-e41
DOI: 10.1055/s-0045-1809064
Artículo de Revisión | Review Article

Triggering Factors of Arthrofibrosis Following Anterior Cruciate Ligament Reconstruction

Article in several languages: español | English
1   Universidad de San Carlos de Guatemala, Ciudad de Guatemala, Guatemala
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1   Universidad de San Carlos de Guatemala, Ciudad de Guatemala, Guatemala
› Author Affiliations

Abstract

Arthrofibrosis corresponds to an intra- and periarticular invasion of fibrous tissue responsible for joint ankylosis. It is a complication that arises due to multiple factors that promote excessive proliferation of myofibroblasts, regulated by reduced apoptosis, adhesions, and aggressive synthesis of extracellular matrix. An incidence of 5–35% has been reported, which is higher in women. The most common triggering factors include the presence of concomitant injuries in the knee joint, limited preoperative range of motion, chronic inflammation in the knee prior to surgery, surgical trauma, errors in surgical technique, postoperative infection, inadequate rehabilitation, and prolonged immobilization after surgery. Understanding the etiology of this condition is essential to identify individuals at higher risk of developing this complication and to develop prevention strategies and appropriate treatment to minimize the risk of arthrofibrosis.

Evidence Level

EBM: Recommendation: Grade A Level of Scientific Evidence: Level IV




Publication History

Received: 19 March 2025

Accepted: 02 April 2025

Article published online:
20 May 2025

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