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DOI: 10.1055/s-0045-1808247
Orbital Metastasis as the Initial Manifestation of Lung Adenocarcinoma: 18F-FDG PET-CT Findings

Abstract
Orbital metastases from malignant tumors are uncommon. In 25% of cases, they are the first sign of an undiagnosed cancer, and they account for approximately 7 to 12% of lung cancer cases. A lack of awareness about this condition can lead to misdiagnosis, distinguishing malignant from benign lesions. We present the case of a 65-year-old patient with orbital metastasis from lung cancer. 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) was crucial in diagnosing this, revealing hypermetabolism in the left lung mass as well as intense uptake in the right retro-orbital region, which was confirmed as orbital metastasis through cerebro-orbital magnetic resonance imaging. For 2 months, our patient had right eye pain and decreased visual acuity and no attention was paid to these symptoms. Through this clinical case, the authors highlight the utility of 18F-FDG PET/CT in the diagnosis of primary malignancy in lung cancer patients, who presented with orbital metastasis as the first sign.
Publikationsverlauf
Artikel online veröffentlicht:
25. April 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
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