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CC BY 4.0 · Indian Journal of Neurotrauma 2025; 22(02): 122-125
DOI: 10.1055/s-0045-1808077
DOI: 10.1055/s-0045-1808077
Review Article
Pathophysiological Mechanisms of Neurogenic Shock
Funding None.
Abstract
Neurogenic shock is caused by damage to the sympathetic nervous system. This can have negative outcomes in the patient, leading to excessive vasodilation, hypotension, and poor circulation. Spinal or brain damage usually continues. Disturbance in autonomous control, reduction in norepinephrine, inflammation, and excess nitrogen oxides are exacerbated. Compensation mechanisms often fail and highlight the need for improved treatment.
Keywords
neurogenic shock - hypotension - spinal cord injury - autonomic dysfunction - vasodilation - sympathetic nervous system - bradycardia - circulation failure - inflammation - nitric oxidePublication History
Article published online:
21 April 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
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