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CC BY 4.0 · Chinese medicine and natural products 2025; 05(01): e59-e72
DOI: 10.1055/s-0045-1807264
Original Article

Meta-analysis of Acupuncture Intervening Benign Prostatic Hyperplasia

Xueyuan Yang
1   Department of Dermatology, the Second Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi, China
2   The Second Clinical Medical College, Xi'an Medical University, Xi'an, Shaanxi, China
,
Wanling Cai
3   Department of Dermatology, Shanghai University of Chinese Medicine Shuguang Hospital, Shanghai, China
,
Wenjuan Yu
1   Department of Dermatology, the Second Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi, China
,
Fang Zhou
1   Department of Dermatology, the Second Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi, China
› Institutsangaben
Funding This work was supported by Institute level project of the Second Affiliated Hospital of Xi'an Medical University (X2Y-R13).
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Abstract

Objective

This study aimed to evaluate the effectiveness of acupuncture for benign prostatic hyperplasia (BPH).

Methods

We searched PubMed, EMBASE, Cochrane Library, Chinese Biomedical Literature Database, Chinese National Knowledge Infrastructure, Wanfang Data, and China Science and Technology Journal Database from their inceptions to February 1, 2022. The language was restricted to English and Chinese. Two researchers independently screened the literature, extracted data, and evaluated the risk bias of the included study according to the Cochrane Handbook 5.1.0. A meta-analysis was performed using Review Manager version 5.3.

Results

Twenty-two studies with 1,765 participants were selected to be incorporated in the meta-analysis. The experimental groups (EGs) showed greater benefit on therapeutic effects (relative risk [RR]: 1.23, 95% CI: 1.16, 1.3; P < 0.00001), International Prostate Score Scale (mean difference [MD]: −2.06, 95% CI: −3.17, −0.96; P = 0.0002), maximum urinary flow rate (MD: 1.7, 95% CI: 0.89, 2.52; P < 0.0001), postvoid residual urine volume (MD: −8.25, 95% CI: −12.14, −4.36; P < 0.0001), quality of life (MD: −0.55, 95% CI: −0.8, −0.29; p < 0.0001) compared with the control groups, whereas for prostate volume (MD: −0.87, 95% CI: −2.66, 0.92; P = 0.34) was not significantly improved in the EGs. Nevertheless, no statistical variation in the reduction of adverse reactions was observed.

Conclusion

Acupuncture therapy, a wildly applied complementary–alternative treatment, may help in the management of BPH.

Keywords

benign prostatic hyperplasia - acupuncture - meta-analysis - systematic review

CRediT Authorship Contribution Statement

Xueyuan Yang: Conceptualization, investigation, formal analysis, and writing—original draft. Wanling Cai: Software, methodology, and data curation. Wenjuan Yu: Supervision, validation, resources, and project administration. Fang Zhou: Writing—review and editing, visualization, and funding acquisition.




Publikationsverlauf

Eingereicht: 27. November 2024

Angenommen: 10. Februar 2025

Artikel online veröffentlicht:
08. April 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany

 

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