Endoscopy 2025; 57(S 02): S126
DOI: 10.1055/s-0045-1805341
Abstracts | ESGE Days 2025
Oral presentation
ERCP strictures: the good, the bad and the ugly 04/04/2025, 15:30 – 16:30 Room 124+125

Factors Influencing Biliary Stent Patency and Clogging Rates Following ERCP

Authors

  • T Moga

    1   Pius Brinzeu County Hospital, Timișoara, Romania
    2   Advanced Regional Research Center in Gastroenterology and Hepatology, Timisoara, Romania

  • B Miutescu

    2   Advanced Regional Research Center in Gastroenterology and Hepatology, Timisoara, Romania

  • R Bende

    2   Advanced Regional Research Center in Gastroenterology and Hepatology, Timisoara, Romania

  • D Vuletici

    2   Advanced Regional Research Center in Gastroenterology and Hepatology, Timisoara, Romania

  • A Voron

    2   Advanced Regional Research Center in Gastroenterology and Hepatology, Timisoara, Romania

  • P Todor

    2   Advanced Regional Research Center in Gastroenterology and Hepatology, Timisoara, Romania

  • C Foncea

    2   Advanced Regional Research Center in Gastroenterology and Hepatology, Timisoara, Romania

  • R Sirli

    2   Advanced Regional Research Center in Gastroenterology and Hepatology, Timisoara, Romania

  • I Ratiu

    2   Advanced Regional Research Center in Gastroenterology and Hepatology, Timisoara, Romania
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Aims Biliary stents are commonly used in ERCP, but their patency and complications vary. This study aimed to identify key factors affecting biliary stent patency within a patient cohort at our center.

Methods A retrospective analysis included patients with obstructive jaundice who underwent ERCP between January 2021 and December 2023, focusing on those who had at least one reintervention within 36 months of initial biliary stent placement.

Results Of 2066 subjects, 53.3% (1102) received biliary stents, primarily plastic (81.2%). Nearly half (48.2%) had prior stenting, with a median reintervention interval of 90 days (range: 1–1095). No significant difference in reintervention timing was noted between malignant (median 75 days) and benign (60 days) etiologies (p=0.3064), or between pancreatic neoplasm and cholangiocarcinoma (60 vs. 90 days, p=0.2025). Univariate regression linked stent clogging to elevated AST (p=0.013), PCR (p=0.023), alkaline phosphatase (p=0.012), choledocholithiasis (p=0.014), purulent bile at ERCP (p=0.001), and acute cholangitis (p=0.001). Multivariate analysis confirmed alkaline phosphatase (p=0.002), purulent bile (p=0.001), and acute cholangitis (p=0.021) as independent predictors. Sphincterotomy, performed in 95% of patients, appeared protective, with a shorter reintervention interval (30 vs. 90 days, p=0.0041) [1].

Conclusions Elevated alkaline phosphatase, purulent bile, and acute cholangitis are significant predictors of biliary stent clogging, while initial sphincterotomy may protect against clogging and extend patency. These insights could inform procedural strategies to improve patient outcomes.



Publication History

Article published online:
27 March 2025

© 2025. European Society of Gastrointestinal Endoscopy. All rights reserved.

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  • References

  • 1 Isayama H, Nakai Y, Kawakubo K, Kogure H, Togawa O, Hamada T, Ito Y, Sasaki T, Yamamoto N, Sasahira N, Hirano K, Tsujino T, Tada M, Koike K.. Covered metallic stenting for malignant distal biliary obstruction: clinical results according to stent type. J Hepatobiliary Pancreat Sci. 2011; 18 (05): 673-7 PMID: 21667054
    CrossrefPubMedSearch in Google Scholar