J Neurol Surg B Skull Base 2025; 86(S 01): S1-S576
DOI: 10.1055/s-0045-1803524
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Endoscopic Endonasal Resection of a GH and Prolactin-Secreting PIT-1 Positive Pituitary Adenoma Invading the Carotico-Clinoid Ligament

Matei A. Banu
1   Stanford University, Stanford, California, United States
,
Vera Vigo
1   Stanford University, Stanford, California, United States
,
Vladimir A. Ljubimov
1   Stanford University, Stanford, California, United States
,
Zara M. Patel
1   Stanford University, Stanford, California, United States
,
Juan Carlos Fernandez-Miranda
1   Stanford University, Stanford, California, United States
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PIT-1 expressing pituitary adenomas have higher predilection for invasion of the cavernous sinus medial wall. We present the case of an incidentally diagnosed PIT-1 positive pituitary adenoma with invasion of the carotico-clinoid ligament (CCL) in a 42-year-old woman with headaches and elevated IGF-1/prolactin levels. Radiographically, the sellar mass appeared to abut the left cavernous ICA. Intraoperative inspection demonstrated infiltration of the CCL which was carefully dissected and removed with normalization of IGF-1/prolactin levels postoperatively.



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Artikel online veröffentlicht:
07. Februar 2025

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