Feasibility of High-Resolution Oximeter Plus Actigraphy Combined with a Cloud-Based Algorithm for the Detection of Obstructive Sleep Apnea in Children with Craniofacial Anomalies

Sergio Henrique Kiemle Trindade; Fábio Luiz Banhara; Leide Vilma Fidélis da Silva; Sara Quaglia de Campos Giampá; Lais Mota Furtado Sena; Ivy Kiemle Trindade-Suedam

doi:10.1055/s-0045-1802967

Sleep Science, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Sleep Sci
DOI: 10.1055/s-0045-1802967

Original Article

Feasibility of High-Resolution Oximeter Plus Actigraphy Combined with a Cloud-Based Algorithm for the Detection of Obstructive Sleep Apnea in Children with Craniofacial Anomalies

Sergio Henrique Kiemle Trindade

¹Sleep Studies Unit, Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil

²Faculdade de Medicina de Bauru, Universidade de São Paulo (FMBRU-USP), Bauru, SP, Brazil

³Department of Otorhinolaryngology, Hospital de Reabilitação de Anomalias Craniofaciais (HRAC), Universidade de São Paulo (USP), Bauru, SP, Brazil

,

Fábio Luiz Banhara

¹Sleep Studies Unit, Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil

,

Leide Vilma Fidélis da Silva

¹Sleep Studies Unit, Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil

,

Sara Quaglia de Campos Giampá

⁴Laboratory of Medical Research on Sleep (LIM/63), Division of Pulmonology, Department of Cardiopulmonology, Instituto do Coração (InCor), Hospital das Clínicas, Faculty of Medicine, Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil

,

Lais Mota Furtado Sena

³Department of Otorhinolaryngology, Hospital de Reabilitação de Anomalias Craniofaciais (HRAC), Universidade de São Paulo (USP), Bauru, SP, Brazil

,

Ivy Kiemle Trindade-Suedam

¹Sleep Studies Unit, Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil

⁵Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru SP, Brazil

› Institutsangaben

Abstract

Objective

To verify the feasibility of high-resolution oximeter plus actigraphy combined with a cloud-based algorithm for the detection of obstructive sleep apnea (OSA) in children with craniofacial anomalies.

Materials and Methods

In the present prospective, cross-sectional study, we evaluated children previously submitted to primary surgical palate repair with a genetically confirmed diagnosis of Treacher Collins syndrome (TCS), non-syndromic Robin sequence (NSRS), or non-syndromic cleft palate (NSCP). The children underwent a clinical evaluation, had their anthropometric measures taken, and were submitted to OSA detection using high-resolution oximeter plus actigraphy combined with a cloud-based algorithm (Biologix Sleep Test, Biologix Sistemas S.A., São Paulo, SP, Brazil).

Results

In total, 64 children (TCS: n = 16; NSRS: n = 29; NSCP: n = 19) were included in the final analysis (mean age: 10 ± 2 years; 64% of female patients). The Biologix Sleep Test showed that 59 patients (92%) presented OSA according to the oxygen desaturation index (ODI): 36 (56%) were diagnosed with mild OSA, 19 (30%), with moderate OSA, and 4 (6%), with severe OSA. The high-resolution oximeter recording showed excellent signal quality in 94.53 ± 5.29% of the exams, with a success rate of exams on the first night of 90%. No significant difference was found in terms of ODI among the subgroups (p > 0.05). A significant relationship was observed between increased ODI with greater hypoxic burden and lower estimated sleep efficiency. The multiple linear regression analysis demonstrated a significant association between changes in total ODI with lower estimated sleep efficiency and sleep ODI.

Conclusion

High-resolution oximeter plus actigraphy combined with a cloud-based algorithm demonstrated adequate feasibility and applicability for OSA detection in children with craniofacial anomalies.

Keywords

oximetry - actigraphy - sleep apnea - obstructive - Treacher Collins syndrome - Pierre Robin syndrome

Bibliographical Record
Sergio Henrique Kiemle Trindade, Fábio Luiz Banhara, Leide Vilma Fidélis da Silva, Sara Quaglia de Campos Giampá, Lais Mota Furtado Sena, Ivy Kiemle Trindade-Suedam. Feasibility of High-Resolution Oximeter Plus Actigraphy Combined with a Cloud-Based Algorithm for the Detection of Obstructive Sleep Apnea in Children with Craniofacial Anomalies. Sleep Sci ; : s00451802967.
DOI: 10.1055/s-0045-1802967

Volltext

Referenzen

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