CC BY 4.0 · Journal of Clinical Interventional Radiology ISVIR
DOI: 10.1055/s-0045-1802654
Case Report

Late Onset Hepatic Encephalopathy after Living Donor Liver Transplant: Successful Reversal by Plug Embolization of Shunt—A Report of Two Cases

1   Interventional Radiology, Max Super Speciality Hospital, Saket, New Delhi, India
,
Dibyalochan Praharaj
2   Centre for Liver and Biliary Sciences, Max Super Speciality Hospital, Saket, New Delhi, India
,
Adnan Khan
1   Interventional Radiology, Max Super Speciality Hospital, Saket, New Delhi, India
,
Subhash Gupta
2   Centre for Liver and Biliary Sciences, Max Super Speciality Hospital, Saket, New Delhi, India
,
1   Interventional Radiology, Max Super Speciality Hospital, Saket, New Delhi, India
› Institutsangaben
Funding None.

Abstract

In liver transplant (LT) recipients, development of portosystemic (PS) shunts can lead to hepatic encephalopathy. Here we report the cases of two patients who presented with hepatic encephalopathy 11 and 15 years after LT. Plug-assisted embolization of PS shunt led to significant improvement in their clinical and neurological symptoms, highlighting the importance of monitoring for PS shunts in long-term LT follow-up.

Ethics Approval and Consent to Participate

Ethical committee approval was not needed for this case report. Informed written consent was taken from the patient.




Publikationsverlauf

Artikel online veröffentlicht:
10. Februar 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Jajodia S, Khandelwal AH, Khandelwal R, Kapoor AK, Baijal SS. Endovascular management of portal steal syndrome due to portosystemic shunts after living donor liver transplantation. JGH Open 2021; 5 (05) 599-606
  • 2 Álvarez-López P, Campos-Varela I, Quiroga S. et al. Spontaneous portosystemic shunt embolization in liver transplant recipients with recurrent hepatic encephalopathy. Ann Hepatol 2022; 27 (03) 100687
  • 3 Zhou HY, Chen TW, Zhang XM, Jing ZL, Zeng NL, Zhai ZH. Patterns of portosystemic collaterals and diameters of portal venous system in cirrhotic patients with hepatitis B on magnetic resonance imaging: association with Child-Pugh classifications. Clin Res Hepatol Gastroenterol 2015; 39 (03) 351-358
  • 4 Kim SH, Lee JM, Choi JY. et al. Changes of portosystemic collaterals and splenic volume on CT after liver transplantation and factors influencing those changes. AJR Am J Roentgenol 2008; 191 (01) W8-W16
  • 5 Kim B, Kim KW, Song GW, Lee SG. Portal flow steal after liver transplantation. Clin Mol Hepatol 2015; 21 (03) 314-317
  • 6 Vijayashanker A, Chikkala BR, Ghimire R. et al. Do natural portosystemic shunts need to be compulsorily ligated in living donor liver transplantation?. J Clin Exp Hepatol 2022; 12 (01) 29-36
  • 7 Hussain N, Bhattacharyya A, Prueksaritanond S. Amiodarone-induced cirrhosis of liver: what predicts mortality?. ISRN Cardiol 2013; 2013: 617943
  • 8 Wang L, Guo X, Xu X. et al. Anticoagulation favors thrombus recanalization and survival in patients with liver cirrhosis and portal vein thrombosis: results of a meta-analysis. Adv Ther 2021; 38 (01) 495-520
  • 9 Gerritzen-Bruning MJ, van den Ingh TS, Rothuizen J. Diagnostic value of fasting plasma ammonia and bile acid concentrations in the identification of portosystemic shunting in dogs. J Vet Intern Med 2006; 20 (01) 13-19