A Retrospective Study Using a Novel Body-Shift Implant Design with a Novel Alloplastic Particulate Grafting Material in Immediate Extraction Sockets

Abstract

With resurgence in immediate tooth replacement therapy (ITRT) as a method of preserving both hard and soft tissues for improved aesthetic outcomes, this multicenter, prospective study looked at two novel products and their effect on those outcomes. Thirty-one maxillary single-tooth implants were included, of these 54.8% were central incisors, 25.8% lateral incisors, and 19.4% canines. Three complications were reported; one case nondraining fistula, one case a nonseated provisional restoration, and one case a fractured zirconia abutment. The definitive restorations were delivered between 4 hours and 18 months postimplant placement and all restorations were screw-retained. ITRT is frequently utilized when a tooth to be extracted will be replaced by an implant aiding in preservation of the hard and soft tissue that may be lost due to resorption during healing of the extraction socket. The narrower neck region of the Inverta implant results in thicker crestal bone around the implant, where loading under function occurs. Grafting that area around the implant at placement with EthOss results in more predictable bone stability in the long term.

Keywords

novel implant design - alloplastic graft materials - immediate tooth replacement

Publikationsverlauf

Artikel online veröffentlicht:
03. Februar 2025

• References

• 1 Levin BP. Advances in esthetic, immediate tooth replacement therapy aimed at improving clinical outcomes. Compend Contin Educ Dent 2023; 44 (08) 472-475
• 2 R T. Kg S, S C, Pandian VB. Clinical and radiographic evaluation of soft tissue and bone status in immediate loaded implants placed following their extraction in the maxillary anterior region. Cureus 2024; 16 (09) e68613
• 3 AlAli F, Atieh MA, Hannawi H. et al. Anterior maxillary labial bone thickness on cone beam computed tomography. Int Dent J 2023; 73 (02) 219-227
• 4 Fugazzotto PA, Baker R, Lightfoot S. Immediate implant therapy in clinical practice: single-tooth replacement. J Mass Dent Soc 2007; 56 (03) 28-32
• 5 Naiem SN, Al-Nawas B, Tawfik OK, El-Nahass H. Jumping gap in immediate implant placement in the esthetic zone: a virtual implant planning using cone-beam computed tomography. J Prosthodont Res 2024; 68 (02) 347-353
• 6 Kabi S, Kar R, Samal D, Deepak KC, Kar IB, Mishra N. Immediate dental implant placement with or without autogenous bone graft: a comparative study. Natl J Maxillofac Surg 2020; 11 (01) 46-52
• 7 Chu SJ. Implant designs in 2020: Current state of the art addresses primary stability. Compend Contin Educ Dent 2020; 41 (08) 432-434
• 8 Norton MR. The influence of insertion torque on the survival of immediately placed and restored single-tooth implants. Int J Oral Maxillofac Implants 2011; 26 (06) 1333-1343
• 9 National Library of Medicine. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. General Assembly of the World Medical Association; 2014
• 10 Gamborena I, Sasaki Y, Blatz MB. et al. The All-at-Once concept: immediate implant placement into fresh extraction sockets with final crown delivery. Quintessense Dent Technol 2019; 42: 165-177
• 11 Elian N, Cho SC, Froum S, Smith RB, Tarnow DP. A simplified socket classification and repair technique. Pract Proced Aesthet Dent 2007; 19 (02) 99-104 , quiz 106
• 12 Miyamoto Y, Obama T. Dental cone beam computed tomography analyses of postoperative labial bone thickness in maxillary anterior implants: comparing immediate and delayed implant placement. Int J Periodontics Restorative Dent 2011; 31 (03) 215-225
• 13 Nevins M, Chu SJ, Jang W, Kim DM. Evaluation of an innovative hybrid macrogeometry dental implant in immediate extraction sockets: a histomorphometric pilot study in foxhound dogs. Int J Periodont Restor Dent 2019; 39 (01) 29-37
• 14 Östman PO, Chu SJ, Drago C, Saito H, Nevins M. Clinical outcomes of maxillary anterior postextraction socket implants with immediate provisional restorations using a novel macro-hybrid implant design: an 18- to 24-month single-cohort prospective study. Int J Periodont Restor Dent 2020; 40 (03) 355-363
• 15 Chu SJ. Inverted body-shift concept in macroimplant design to enhance biologic and esthetic outcomes: a clinical report. J Prosthet Dent 2021; 126 (06) 720-726
• 16 Albrektsson T, Wennerberg A. Oral implant surfaces: part 1 - review focusing on topographic and chemical properties of different surfaces and in vivo responses to them. Int J Prosthodont 2004; 17 (05) 536-543
• 17 Leventis MD, Fairbairn P, Dontas I. et al. Biological response to β-tricalcium phosphate/calcium sulfate synthetic graft material: an experimental study. Implant Dent 2014; 23 (01) 37-43
• 18 Leventis MD, Fairbairn P, Kakar A. et al. Minimally invasive alveolar ridge preservation utilizing an in situ hardening β-tricalcium phosphate bone substitute. A multicenter case series. Int J Dent 2016; 2016: 5406736
• 19 Habibovic A, Malhotra P. Calcium phosphates and angiogenesis: implications and advances for bone regeneration. Trends Biotechnol 2018; 34: 12
• 20 Miron RJ, Zhang Q, Sculean A. et al. Osteoinductive potential of 4 commonly employed bone grafts. Clin Oral Investig 2016; 20 (08) 2259-2265
• 21 Flifl MAS, Marzook H, Denewar M, Elsheikh HAE. Biological impact of alloplastic bone graft vs bovine xenograft and allograft materials in bone healing: an experimental study. J Contemp Dent Pract 2022; 23 (05) 482-491
• 22 Bohner M, Santoni BLG, Döbelin N. β-tricalcium phosphate for bone substitution: synthesis and properties. Acta Biomater 2020; 113: 23-41
• 23 Kamitakahara M, Ohtsuki C, Miyazaki T. Review paper: behavior of ceramic biomaterials derived from tricalcium phosphate in physiological condition. J Biomater Appl 2008; 23 (03) 197-212
• 24 Yip I, Ma L, Mattheos N, Dard M, Lang NP. Defect healing with various bone substitutes. Clin Oral Implants Res 2015; 26 (05) 606-614
• 25 Liu CC, Solderer A. et al. Tricalcium phosphate (containing) biomaterials in the treatment of periodontal infra-bony defects: a systemic review and meta-analysis. J Dent 2021; 114: 103812
• 26 Braut V, Bornstein MM, Belser U, Buser D. Thickness of the anterior maxillary facial bone wall-a retrospective study using cone beam computerised tomography. J Periodontics Restorative Dentistry 2011; 31 (02) 125-131
• 27 Östman PO, Hellman M, Sennerby L. Direct implant loading in the edentulous maxilla using a bone density-adapted surgical protocol and primary implant stability criteria for inclusion. Clin Implant Dent Relat Res 2005; 7 (Suppl. 01) S60-S69
• 28 Steigmann M, Monje A, Chan HL, Wang HL. Emergence profile design based on implant position in the esthetic zone. Int J Periodont Restor Dent 2014; 34 (04) 559-563
• 29 Fürhauser R, Florescu D, Benesch T, Haas R, Mailath G, Watzek G. Evaluation of soft tissue around single-tooth implant crowns: the pink esthetic score. Clin Oral Implants Res 2005; 16 (06) 639-644
• 30 Chappuis V, Bornstein MM, Buser D, Belser U. Influence of implant neck design on facial bone crest dimensions in the esthetic zone analyzed by cone beam CT: a comparative study with a 5-to-9-year follow-up. Clin Oral Implants Res 2016; 27 (09) 1055-1064
• 31 Chu SJ, Östman PO, Nicolopoulos C. et al. Prospective muticenter clinical cohort study of a novel macro hybrid implant in maxillary anterior postextraction sockets: 1-year results. Int J Periodont Restor Dent 2018; 38 (Suppl): s17-s27
• 32 Blanco J, Nuñez V, Aracil L, Muñoz F, Ramos I. Ridge alterations following immediate implant placement in the dog: flap versus flapless surgery. J Clin Periodontol 2008; 35 (07) 640-648
• 33 Covani U, Bortolaia C, Barone A, Sbordone L. Bucco-lingual crestal bone changes after immediate and delayed implant placement. J Periodontol 2004; 75 (12) 1605-1612
• 34 Covani U, Cornelini R, Barone A. Bucco-lingual bone remodeling around implants placed into immediate extraction sockets: a case series. J Periodontol 2003; 74 (02) 268-273
• 35 Qahash M, Susin C, Polimeni G, Hall J, Wikesjö UME. Bone healing dynamics at buccal peri-implant sites. Clin Oral Implants Res 2008; 19 (02) 166-172
• 36 Vignoletti F, de Sanctis M, Berglundh T, Abrahamsson I, Sanz M. Early healing of implants placed into fresh extraction sockets: an experimental study in the beagle dog. II: ridge alterations. J Clin Periodontol 2009; 36 (08) 688-697
• 37 Chen ST, Buser D. Esthetic outcomes following immediate and early implant placement in the anterior maxilla–a systematic review. Int J Oral Maxillofac Implants 2014; 29 (Suppl): 186-215
• 38 Chu SJ, Saito H, Östman PO, Levin BP, Reynolds MA, Tarnow DP. Immediate tooth replacement therapy in postextraction sockets: a comparative prospective study on the effect of variable platform-switched subcrestal angle correction implants. Int J Periodont Restor Dent 2020; 40 (04) 509-517
• 39 Gluckman H, Salama M, Du Toit J. Partial extraction therapies (PET) part 2: procedures and technical aspects. Int J Periodont Restor Dent 2017; 37 (03) 377-385
• 40 Kurtzman GM, Dompkowski DF, Mahler BA, Howes DG. Off-axis implant placement for anatomical considerations using the co-axis implant. Inside Dentistry 2008; 4 (05) 2-5
• 41 Ortega-Martínez J, Pérez-Pascual T, Mareque-Bueno S, Hernández-Alfaro F, Ferrés-Padró E. Immediate implants following tooth extraction. A systematic review. Med Oral Patol Oral Cir Bucal 2012; 17 (02) e251-e261
• 42 Tarnow DP, Chu SJ, Salama MA. et al. Flapless postextraction socket implant placement in the esthetic zone: part 1. The effect of bone grafting and/or provisional restoration on facial-palatal ridge dimensional change-a retrospective cohort study. Int J Periodontics Restorative Dent 2014; 34 (03) 323-331
• 43 Yang HL, Zhu XS, Chen L. et al. Bone healing response to a synthetic calcium sulfate/β-tricalcium phosphate graft material in a sheep vertebral body defect model. J Biomed Mater Res B Appl Biomater 2012; 100 (07) 1911-1921
• 44 Retzepi M, Donos N. Guided bone regeneration: biological principle and therapeutic applications. Clin Oral Implants Res 2010; 21 (06) 567-576
• 45 Benic GI, Hämmerle CHF. Horizontal bone augmentation by means of guided bone regeneration. Periodontol 2000 2014; 66 (01) 13-40
• 46 Jung RE, Fenner N, Hämmerle CH, Zitzmann NU. Long-term outcome of implants placed with guided bone regeneration (GBR) using resorbable and non-resorbable membranes after 12-14 years. Clin Oral Implants Res 2013; 24 (10) 1065-1073
• 47 Roberts SJ, van Gastel N, Carmeliet G, Luyten FP. Uncovering the periosteum for skeletal regeneration: the stem cell that lies beneath. Bone 2015; 70: 10-18
• 48 Weng D, Hürzeler MB, Quiñones CR, Ohlms A, Caffesse RG. Contribution of the periosteum to bone formation in guided bone regeneration. A study in monkeys. Clin Oral Implants Res 2000; 11 (06) 546-554
• 49 Colnot C. Skeletal cell fate decisions within periosteum and bone marrow during bone regeneration. J Bone Miner Res 2009; 24 (02) 274-282
• 50 Theodoropoulou E, Horowitz R, Kalyvas D. Evaluation of an in situ hardening β-tricalcium phosphate graft material for alveolar ridge preservation. A histomorphometric animal study in pigs. Dent J (Basel) 2018; 06 (03) 27
• 51 Wang Q, Huang C, Xue M, Zhang X. Expression of endogenous BMP-2 in periosteal progenitor cells is essential for bone healing. Bone 2011; 48 (03) 524-532
• 52 Samee M, Kasugai S, Kondo H, Ohya K, Shimokawa H, Kuroda S. Bone morphogenetic protein-2 (BMP-2) and vascular endothelial growth factor (VEGF) transfection to human periosteal cells enhances osteoblast differentiation and bone formation. J Pharmacol Sci 2008; 108 (01) 18-31
• 53 Buser D, Chappuis V, Belser UC, Chen S. Implant placement post extraction in esthetic single tooth sites: when immediate, when early, when late?. Periodontol 2000 2017; 73 (01) 84-102
• 54 Dawson A, Martin WC, Polido WD. The SAC classification in implant dentistry. Berlin, Germany: Quintessenz Verlag; 2022
• 55 al Ruhaimi KA. Effect of calcium sulphate on the rate of osteogenesis in distracted bone. Int J Oral Maxillofac Surg 2001; 30 (03) 228-233
• 56 Sasaki H, Koyama S, Yokoyama M, Yamaguchi K, Itoh M, Sasaki K. Bone metabolic activity around dental implants under loading observed using bone scintigraphy. Int J Oral Maxillofac Implants 2008; 23 (05) 827-834
• 57 Leventis M, Fairbairn P, Mangham C. et al. Bone healing in rabbit calvaria defects using a synthetic bone substitute: a histological and micro-CT comparative study. Materials (Basel) 2018; 11 (10) 2004
• 58 Chan HL, Lin GH, Fu JH, Wang HL. Alterations in bone quality after socket preservation with grafting materials: a systematic review. Int J Oral Maxillofac Implants 2013; 28 (03) 710-720
• 59 Tarnow D, Elian N, Fletcher P. et al. Vertical distance from the crest of bone to the height of the interproximal papilla between adjacent implants. J Periodontol 2003; 74 (12) 1785-1788
• 60 Wolff J. The Law of Bone Remodelling. Berlin, Germany: Springer; 1892
• 61 Fairbairn P, Leventis M, Mangham C, Horowitz R. Alveolar ridge preservation using a novel synthetic grafting material; a case study with 2 year follow up. Case Rep Dent 2018; 2018: 6412806