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CC BY-NC-ND 4.0 · Asian J Neurosurg 2025; 20(02): 236-240
DOI: 10.1055/s-0044-1801281
Original Article

Isolated Mega Cisterna Magna: A Preliminary Study from Eastern Iran

Masoud Pishjoo
1   Department of Neurosurgery, Shohada Hospital, Ghaen, South Khorasan, Iran
,
Mohammad Safdari
2   Department of Neurosurgery, Zahedan University of Medical Sciences, Zahedan, Iran
,
Zohre Safdari
3   Department of Radiology, Shohada Hospital, Ghaen, South Khorasan, Iran
,
Mahtab Ghaemi
4   Department of Internal Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
,
Daniel Kheradmand
5   Department of Neurosurgery, Birjand University of Medical Sciences, Birjand, Iran
,
Ali Fathi Jouzdani
6   Neuroscience and Artificial Intelligence Research Group, Department of Neuroscience, Hamadan University of Medical Sciences, Hamadan, Iran
,
Sajjad Saghbdoust
7   Department of Neurosurgery, Razavi Hospital, Mashhad, Iran
› Institutsangaben
Funding None.
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Abstract

Background The clinical significance and incidence of isolated mega cisterna magna (MCM) have been thoroughly investigated. While MCM has been reported in association with psychiatric disorders in adults, current study sought to report its incidence and relationship with gender and age in a consecutive series of patients without psychiatric comorbidities.

Materials and Methods We retrospectively reviewed 1,016 consecutive computed tomography scans of patients between the age of 1 and 80 with a history of minor head trauma, headache, or vertigo from April to August 2023. Two perpendicular diameters inside the MCM were measured: the first diameter (D1) was measured longitudinally on the midsagittal plane (anteroposterior diameter), whereas the second one (D2) was measured transeversely (transverse diameter). An MCM with D1 > 20 mm was defined as “huge MCM.” The relationship between age, gender, and the two diameters were subsequently analyzed.

Results Over a course of 5 months, 92 cases with MCM, including 76 men, were evaluated. The mean age of MCM cases was 35.31 ± 26.14, with no significant relationship observed between age and MCM. No significant difference in D1 was found between genders, while D2 significantly differed between men and women (p < 0.029). “Huge MCM” was exclusively observed in 18 men (p < 0.035). There was also no significant correlation between D1 and D2.

Conclusion MCM appears to be a normal variation in the general population with no clinical significance. Despite the small sample size, the current study can provide a foundation for further studies to investigate the correlation of isolated MCM with different aspects of cognitive functions and its potential clinical relevance.

Keywords

computed tomography scan - mega cisterna magna - normal population - normal variation - preliminary study


Publikationsverlauf

Artikel online veröffentlicht:
17. Januar 2025

© 2025. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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