Local Administration of Antibiotics in Orthopedics and Traumatology

Yves Gramlich; Matthias Schnetz; Reinhard Hoffmann

doi:10.1055/s-0044-1800907

The Journal of Hip Surgery, Inhaltsverzeichnis

The Journal of Hip Surgery 2024; 08(03): 163-182
DOI: 10.1055/s-0044-1800907

CME-Advanced Training

Local Administration of Antibiotics in Orthopedics and Traumatology

Lokale Antibiotikatherapie in der Orthopädie und Unfallchirurgie

Yves Gramlich

,

Matthias Schnetz

,

Reinhard Hoffmann

Abstract

2022 marks the 50th anniversary of the development of the antibiotic loaded PMMA chain. The loading of bone cements with antibiotics was a major advance in the treatment of musculoskeletal infections and is still a proven standard today. The research and use of novel antibiotic carriers continues to be an important part of research in the context of musculoskeletal infections. The article provides an overview of the various local antibiotics available and their specifics. In addition, current adapted treatment concepts are discussed.

Zusammenfassung

2022 jährte sich die Entwicklung der Antibiotikakette zum 50. Mal. Die Beladung von Knochenzementen mit Antibiotika war ein herausragender Fortschritt in der Behandlung muskuloskelettaler Infektionen; das Verfahren ist heute noch bewährter Standard. Die Erforschung wie auch Verwendung neuartiger Antibiotikaträger ist weiterhin ein wichtiger Bestandteil der Forschung im Kontext muskuloskelettaler Infektionen. Der Artikel gibt einen Überblick über die verschiedenen erhältlichen lokalen Antibiotika und deren Spezifika. Darüber hinaus werden aktuelle angepasste Behandlungskonzepte besprochen.

Keywords

antibiotic carrier - PMMA - antibiotic beads - musculoskeletal infection - Periprosthetic joint Infection - PJI - fracture related infection - FRI - local antibiotics

Schlüsselwörter

Antibiotikaträger - PMMA - Antibiotikakette - muskuloskelettale Infektion - periprothetische Infektion - implantatassoziierte Infektion - lokale Antibiotikatherapie - Cerament

Volltext

Referenzen

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