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CC BY 4.0 · European Journal of General Dentistry 2025; 14(02): 122-135
DOI: 10.1055/s-0044-1793851
Review Article

The Association between Dental Caries and Cardiovascular Disease: A Scoping Review

Atik Ramadhani 
1   Department of Dental Public Health and Preventive Dentistry, Faculty of Dentistry Universitas Indonesia, Depok, Indonesia
,
Vita Vianti 
1   Department of Dental Public Health and Preventive Dentistry, Faculty of Dentistry Universitas Indonesia, Depok, Indonesia
,
Iwany Amalliah Badruddin 
1   Department of Dental Public Health and Preventive Dentistry, Faculty of Dentistry Universitas Indonesia, Depok, Indonesia
,
Armasastra Bahar 
1   Department of Dental Public Health and Preventive Dentistry, Faculty of Dentistry Universitas Indonesia, Depok, Indonesia
,
Normaliza Ab Malik 
2   Department of Conservative Dentistry and Prosthodontic, Faculty of Dentistry, Universiti Sains Islam Malaysia, Bandar Baru Nilai, Nilai, Malaysia
,
Anton Rahardjo 
1   Department of Dental Public Health and Preventive Dentistry, Faculty of Dentistry Universitas Indonesia, Depok, Indonesia
› Author Affiliations Funding The publication of this research was funded by the Faculty of Dentistry, Universitas Indonesia.
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Abstract

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Several epidemiological studies have reported oral health as one of the risk factors for CVD. This scoping review aimed to present evidence from published reports regarding the association between dental caries and CVD incidence. The search strategy was conducted using available databases (PubMed, Scopus, and ProQuest) for studies published from January 2013 to December 2023 in the English language. The retrieved articles were further evaluated according to the inclusion and exclusion criteria, and 24 relevant articles were selected for review to support the evidence based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for scoping review guidelines. Furthermore, 12 cross-sectional, 5 case-control, and 7 cohort studies reported a correlation between dental caries and CVD incidence. The results of this review suggest an association between dental caries and CVD through oral infection or pathogen-induced oral inflammatory mediators. Moreover, other potential factors that increase the risk of CVD include age, hypertension, tobacco smoking, diabetes mellitus, stress, genetic predisposition, physical activity, alcohol consumption, health behaviors, obesity, antibiotic supplementation, awareness of oral health, access to health care, nutrition, and low socioeconomic status. Despite the limited number of studies, there is much evidence of an association between dental caries and CVD incidence. Understanding the association between dental caries and CVD plays a pivotal role in patient education and treatment planning. To expand the search source and evidence, future systematic reviews and meta-analyses should investigate the associations between dental caries and CVD.

Keywords

atherosclerosis - decayed teeth - heart disease - stroke


Publication History

Article published online:
11 December 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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