PDF icon PDF herunterladen
Open Access
CC BY 4.0 · Arch Plast Surg 2025; 52(01): 021-024
DOI: 10.1055/s-0044-1792022
Breast/Trunk
Case Report

Malignant Pilomatricoma with Lung Metastases: A Case Report and Literature Review

Nae-Ho Lee 
1   Department of Plastic and Reconstructive Surgery, Medical School of Jeonbuk National University, Jeonju, Republic of Korea
2   Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Republic of Korea
,
Jung Kyun Park 
1   Department of Plastic and Reconstructive Surgery, Medical School of Jeonbuk National University, Jeonju, Republic of Korea
2   Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Republic of Korea
,
Si-Gyun Roh 
1   Department of Plastic and Reconstructive Surgery, Medical School of Jeonbuk National University, Jeonju, Republic of Korea
2   Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Republic of Korea
,
Jin Yong Shin 
1   Department of Plastic and Reconstructive Surgery, Medical School of Jeonbuk National University, Jeonju, Republic of Korea
2   Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Republic of Korea
,
Yoon Kyu Chung 
1   Department of Plastic and Reconstructive Surgery, Medical School of Jeonbuk National University, Jeonju, Republic of Korea
2   Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Republic of Korea
,
Kyu Yun Jang 
3   Department of Pathology, Medical School of Jeonbuk National University, Jeonju, Republic of Korea
› Institutsangaben
› Weitere Informationen
  Lizenzen und Reprints
Preview

Abstract

Malignant pilomatricoma, an extremely rare tumor arising from hair follicles, most commonly occurs on the head, neck, and back. This tumor exhibits several noteworthy characteristics. First, it frequently recurs if it is incompletely excised and can occasionally metastasize to the lungs, bones, and lymph nodes. Additionally, it possesses unique histological features that aid in differentiating it from its benign counterpart, including atypical cells, multiple mitoses with ghost cells, nuclear polymorphisms, and necrosis accompanied by serial desmoplasia. While no definitive criteria have been established for the surgical management of this malignant tumor, it is recommended to perform wide local excision with a safety margin of at least ≥5 mm. To the best of our knowledge, very few cases of malignant pilomatricoma with lung metastasis have been reported in Korea. Here we report the case of a patient diagnosed of malignant pilomatricoma with lung metastasis who underwent wide local excision for a lesion on the flank.

Keywords

malignant pilomatricoma - lung metastasis - case reports

Authors' Contributions

Conceptualization: S-G.R.


Data curation: J.K.P.


Writing—original draft: S-G.R., J.K.P.


Writing—review and editing: S-G.R., N-H.L., J.Y.S., Y.K.C.


Supervision: S-G.R.


All authors read and approved the final manuscript.


Patient Consent

Written informed consent was obtained from patient.


Ethical Approval

This study was conducted in compliance with the Declaration of Helsinki




Publikationsverlauf

Eingereicht: 01. September 2023

Angenommen: 23. September 2024

Artikel online veröffentlicht:
24. Dezember 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA