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CC BY 4.0 · Int Arch Otorhinolaryngol 2025; 29(01): s00441791730
DOI: 10.1055/s-0044-1791730
Original Research

Comparison of Graft Uptake in Perforated Eardrums with and without Myringosclerosis: A Prospective Case-control Study in a Tertiary Centre

Ayaz Rehman
1   Department of Otorhinolaryngology, Head and Neck Surgery, SKIMS Medical College and Hospital, Srinagar, Jammu and Kashmir, India
,
Faizah Ashfah Latief Deva 
1   Department of Otorhinolaryngology, Head and Neck Surgery, SKIMS Medical College and Hospital, Srinagar, Jammu and Kashmir, India
,
Asef Ahmad Wani
1   Department of Otorhinolaryngology, Head and Neck Surgery, SKIMS Medical College and Hospital, Srinagar, Jammu and Kashmir, India
,
Majid Masoodi
1   Department of Otorhinolaryngology, Head and Neck Surgery, SKIMS Medical College and Hospital, Srinagar, Jammu and Kashmir, India
,
Bashir Malik
1   Department of Otorhinolaryngology, Head and Neck Surgery, SKIMS Medical College and Hospital, Srinagar, Jammu and Kashmir, India
,
Owais Makhdoomi
1   Department of Otorhinolaryngology, Head and Neck Surgery, SKIMS Medical College and Hospital, Srinagar, Jammu and Kashmir, India
› Institutsangaben
Funding The authors declare that they did not receive financial support from agencies in the public, private or non-profit sectors to conduct the present study.
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Abstract

Introduction Various factors have been reported to affect the rates of success after tympanoplasty, among them, myringosclerosis. However, there are few studies focusing only on the effect of myringosclerotic plaque removal on tympanoplasty outcomes.

Objective To compare the outcome of tympanoplasty in perforated eardrums with and without myringosclerosis.

Methods The study included patients aged between 21 and 53 years diagnosed at the outpatient department with inactive mucosal chronic otitis media. The sample was divided into the case group, which included subjects with tympanic membrane perforation and myringosclerosis, and the control group, which included subjects with tympanic membrane perforation only, without myringosclerosis. We assessed the audiological findings of the patients before and after surgery, as well as hearing gain, graft uptake, and residual perforation/reperforation.

Results No significant relationships were observed involving the age or sex of the patient and the closure rate or hearing gain, neither between the location of the perforation and graft uptake. Graft uptake was higher in patients with perforation size < 50%. The graft uptake and hearing gain were higher in the case group.

Conclusion The removal of sclerotic plaques increases the surface of the raw area created by subepithelial excision of the myringosclerotic plaques, leading to a high rate of surgical success for the closure of tympanic membrane defects with coexisting myringosclerosis.

Keywords

otitis media - tympanic membrane perforation - sclerosis - tympanoplasty - uptake - outcome

Ethics Approval

The present study was approved by the institutional Ethics committee (IEC/60/2019), and the study adhered to the tenets of the Declaration of Helsinki.


Consent to Participate

Informed consent was obtained from all participants included in the present study.


Authors' Contributions

All authors contributed to the study's conception and design, commented on previous versions of the manuscript, and read and approved the final manuscript. FD: material preparation, data collection, analysis, and writing of the first draft of the manuscript.




Publikationsverlauf

Eingereicht: 15. Mai 2024

Angenommen: 21. August 2024

Artikel online veröffentlicht:
31. Januar 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)

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Bibliographical Record
Ayaz Rehman, Faizah Ashfah Latief Deva, Asef Ahmad Wani, Majid Masoodi, Bashir Malik, Owais Makhdoomi. Comparison of Graft Uptake in Perforated Eardrums with and without Myringosclerosis: A Prospective Case-control Study in a Tertiary Centre. Int Arch Otorhinolaryngol 2025; 29: s00441791730.
DOI: 10.1055/s-0044-1791730