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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2025; 35(02): 263-271
DOI: 10.1055/s-0044-1791491
Original Article

Safety Clearance and Artifact Testing of a Nitinol Breast Biopsy Clip in an Ultra-High Resolution (7 Tesla) Magnetic Resonance Imaging Environment

William Dong
1   Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States
,
Kanchna Ramchandran
1   Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States
,
Adam E. Galloy
2   Roy J. Carver Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, Iowa, United States
,
Marco A. Nino
2   Roy J. Carver Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, Iowa, United States
,
Marla Kleingartner
3   Magnetic Resonance Research Facility, University of Iowa, Iowa City, Iowa, United States
,
John Piaszynski
1   Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States
,
Madhavan L. Raghavan
2   Roy J. Carver Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, Iowa, United States
,
Sneha Phadke
1   Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States
,
Vincent A. Magnotta
4   Department of Radiology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States
› Institutsangaben
Funding We would also like to acknowledge the Fraternal Order of Eagles Cancer Fund, for supporting this research. We would like to acknowledge the funding from NIH in support of the scanner used to collect these data (grant no.: S10RR028821). V.A.M. receives partial salary support from the NIH P50HD103556 grant. K.R. received partial salary support from the Benz grant from the Holden Comprehensive Cancer Center during this study. W.D. received scholarship funding from the University of Iowa's Maximizing Access to Research Careers Program, funded by NIH (grant no.: T34GM141143).
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Abstract

Background The lack of safety clearance of several metallic breast biopsy clips in 7 Tesla (T) poses a significant hurdle to using advanced magnetic resonance imaging (MRI) techniques in clinical management or cancer research.

Aims This article assesses the Ultracor Twirl clip for safety and imaging artifacts in a 7T MRI scanner.

Setting and Design This study can be categorized as a phantom study.

Materials and Methods Tests for magnetic susceptibility (translational attraction and torque), MRI-related heating, and artifacts were conducted based on the American Society for Testing and Materials standards. The magnetic susceptibility tests evaluated the scanner's magnetic force that can cause clip movement and rotation. The heating test was conducted with customized MRI parameters of short TR and maximum echo-train length, designed to induce temperature change. The artifact test, using T1-weighted spin and gradient echo imaging sequences, evaluated potential image misrepresentations (localized signal loss) caused by the clip's metallic properties.

Statistical Tests None.

Results and Conclusion The magnetic susceptibility tests indicated no noticeable translational or rotational force exerted by the MRI scanner. The heating test indicated no significant temperature change (<0.3°C) in the testing gel when the clip was absent/present, both within the safety threshold (<1°C). The artifact test's clip images all contained an artifact (largest radius = 10.7 mm). These cumulative results indicate that this clip is safe in 7T scanners. Scanning at least 10.7 mm away from the clip avoids potential signal loss in the region of interest.

Keywords

7T MRI - safety test - artifact test

Note

This work is attributed to the Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa, United States.


Supplementary Material



Publikationsverlauf

Artikel online veröffentlicht:
07. Oktober 2024

© 2024. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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