Abstract
Background Chorioangiomas are benign vascular placental tumors. Although most of them remain
small and are asymptomatic, large tumors (>4 cm) may cause maternal or fetal complications.
Methods We report seven cases of chorioangioma over a span of 8 years in a single tertiary
center managed either conservatively or with necessary intervention. All cases were
followed up and postnatal outcomes were recorded.
Results Six cases were diagnosed in the second trimester and one in the third trimester by
ultrasound. Four were managed conservatively, while three of them required prenatal
therapy: one interstitial laser and the other two an intrauterine arterial embolization
of the feeder vessel. One underwent a rescue intrauterine fetal transfusion before
definitive embolization. Conservatively managed patients developed gestational hypertension
and growth restriction. They had low birth weight and needed neonatal intensive care.
There was one intrauterine demise (IUD) and two healthy neonates in the cases that
needed a fetal intervention.
Conclusion The management of chorioangioma is dynamic and challenging, ranging from conservative
to prenatal intervention. Treatment failure can result in serious complications adversely
affecting pregnancy outcomes. However, regular monitoring by ultrasound and Doppler
surveillance with timely interventions can lead to good neonatal and maternal outcomes.
Keywords
chorioangioma - embolization - prenatal intervention
