Clinicopathological Analysis and Survival of Patients with Cervical Cancer Submitted to Pelvic Exenteration

Abstract

Justification The importance of this study arises from the high incidence and mortality of cervical cancer (CC), and the need to evaluate the effectiveness of current treatments, such as pelvic exenteration, performed in cases of persistent or recurrent carcinoma.

Objective To analyze the relationship between clinical and pathological factors and the results of mortality and recurrence in patients with CC who underwent pelvic exenteration at the Hospital Haroldo Juaçaba, from 2000 to 2019, aiming to improve the understanding of this procedure's outcomes.

Materials and Methods Observational, cross-sectional, retrospective study, using medical record consultation.

Results Patients with perineural invasion, those with prior surgical treatment, and those who underwent radical surgery had lower disease-free survival rates. Also, patients over 50-years-old had lower overall survival than those under that age range.

Conclusion Pelvic exenteration is a high-risk treatment for malignant pelvic neoplasms, with results influenced by technique and institutional resources. Despite the risks, it can control the disease in the long term and even cure it. However, it can affect quality of life and sexual function. Young patients should be made aware of CC prevention methods.

Keywords

cervical cancer - pelvic exenteration - survival

Author's Contribution

BMPA: data collection, assembly, analysis, and interpretation, study conception and design, writing and final approval of the manuscript, provision of study materials or patients. FLM: data analysis and interpretation, final approval of the manuscript. HFCN: writing and final approval of the manuscript, provision of study materials or patient. BSS: collection and assembly of data, final approval of the manuscript. JSO: collection and assembly of data, study conception and design.

Publikationsverlauf

Eingereicht: 05. Mai 2024

Angenommen: 18. Juli 2024

Artikel online veröffentlicht:
28. September 2024

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