Download PDF
Open Access
CC BY-NC-ND 4.0 · South Asian J Cancer 2025; 14(03): 517-519
DOI: 10.1055/s-0044-1789604
Case Report
Breast Cancer Section

Primary Breast Lymphoma: A Rare but Important Differential Diagnosis in Patients with Breast Malignancy

Authors

  • Irappa Madabhavi

    1   Department of Medical and Pediatric Oncology and Hematology, J. N. Medical College and KLE Academy of Higher Education and Research, Belagavi, Karnataka, India
    2   Department of Medical and Pediatric Oncology and Hematology, Kerudi Cancer Hospital, Bagalkot, Karnataka, India
    3   Nanjappa Hospital, Davanagere, Karnataka, India

  • Malay Sarkar

    4   Department of Pulmonary Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India

  • Raghavendra Sagar

    5   Department of Radiation Oncology, J. N. Medical College, Belagavi, Karnataka, India

  • Swaroop Revannasiddaiah

    6   Department of Medical Oncology and Hematology, Sagar Hospitals, Bangalore, Karnataka, India

  • Vineet Kumar

    7   Department of Community Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
Further Information
Also available at
  Permissions and Reprints

Abstract

This report is based upon the case of a young lady who presented with a history of a breast lump, which despite clinically resembling a carcinoma, was subsequently diagnosed to be a primary breast lymphoma (PBL). Though rare in incidence, PBL may masquerade as breast carcinoma. PBL accounts for about 1.7–2.2% of all extranodal non-Hodgkin's lymphoma, and is accountable for up to 0.5% of all breast malignancies. Given that the treatments of breast carcinoma and PBL are markedly different, it is very essential that core-biopsy be preferred in every patient being evaluated for carcinoma of the breast. The diagnosis of diffuse large B cell lymphoma (DLBCL) was confirmed by immunohistochemistry, and the patient has been treated with six-cycles of chemotherapy followed by involved field-radiotherapy to the right breast. After a year's follow-up, the patient remains free of disease.

Keywords

breast lymphoma - CHOP - chemotherapy - radiotherapy

Authors’ Contributions

I.M. conceived and designed the experiment, made critical revisions, and approved the final version. I.M., M.S., V.K., and R.S. analyzed the data and wrote the first draft of the manuscript. I.M., M.S., V.K., and R.S. contributed to the writing of the manuscript. I.M., M.S., V.K., and R.S. agree with the manuscript results and conclusions. I.M., M.S., V.K., and R.S. jointly developed the structure and arguments for the paper. All authors reviewed and approved the final manuscript.




Publication History

Received: 26 March 2024

Accepted: 26 July 2024

Article published online:
29 August 2024

© 2024. MedIntel Services Pvt Ltd. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India