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DOI: 10.1055/s-0044-1789210
Epidemiological, Clinical, Etiological, and Therapeutic Aspects of Cerebral Palsy in Dakar
Abstract
Cerebral palsy is one of the most frequent causes of motor disability in children. The aim of our study was to characterize the epidemiological, clinical, paraclinical, etiological, and therapeutic aspects in Dakar. This was a retrospective and descriptive study from March 2010 to March 2020 at the Albert Royer National Children's Hospital and the Neurology Department of the Fann National University Hospital. We collected 913 patients, 13.7% of all pediatric neurology consultations, out of which 556 (60.9%) were males. The average age of the patients was 32.99 months (ranging between 25 days and 17 years). The most common subtype was isolated axial hypotonia (50%) followed by pyramidal (40.5%) and 45% had epilepsy. Brain imaging revealed cortico-subcortical atrophy in 15% of cases. Five hundred and fifty-two children (60.5%) had an electroencephalogram out of which 19.4% had diffuse irritative anomalies. In terms of treatment, 73% had received motor kinesitherapy. Sodium valproate was the most commonly used antiseizure medication at 76.67%. The average follow-up was 12 months. Seven hundred and ninety-two children (86.8%) were lost to follow-up and 5 children (0.5%) died. Psychomotor development improved in 219 children (13.4%) who acquired standing. Note that 267 children (30%) in a stable sitting position and 29 children had acquired language. Cerebral palsy is a disabling condition that needs to be diagnosed early and early interventions can improve the quality of life of the child.
Publication History
Received: 08 October 2023
Accepted: 16 July 2024
Article published online:
23 August 2024
© 2024. Thieme. All rights reserved.
Georg Thieme Verlag KG
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References
- 1 Vitrikas K, Dalton H, Breish D. Cerebral palsy: an overview. Am Fam Physician 2020; 101 (04) 213-220
- 2 Kakooza-Mwesige A, Andrews C, Peterson S, Wabwire Mangen F, Eliasson AC, Forssberg H. Prevalence of cerebral palsy in Uganda: a population-based study. Lancet Glob Health 2017; 5 (12) e1275-e1282
- 3 El-Tallawy HN, Farghaly WM, Shehata GA. et al. Cerebral palsy in Al-Quseir City, Egypt: prevalence, subtypes, and risk factors. Neuropsychiatr Dis Treat 2014; 10: 1267-1272
- 4 El-Tallawy HN, Farghaly WMA, Shehata GA, Metwally NA, Rageh TA, Abo-Elfetoh N. Epidemiology of cerebral palsy in El-Kharga District-New Valley (Egypt). Brain Dev 2011; 33 (05) 406-411
- 5 Ndiaye M, Tall I, Basse AM. et al. Infirmite motrice d'origine cerebrale: une serie Senegalaise. Afr J Neurol Sci 2012; 31: 15-22
- 6 Himmelmann K, Horber V, De La Cruz J. et al; SCPE Working Group. MRI classification system (MRICS) for children with cerebral palsy: development, reliability, and recommendations. Dev Med Child Neurol 2017; 59 (01) 57-64
- 7 Chen D, Huang M, Yin Y. et al. Risk factors of cerebral palsy in children: a systematic review and meta-analysis. Transl Pediatr 2022; 11 (04) 556-564
- 8 Erkin G, Delialioglu SU, Ozel S, Culha C, Sirzai H. Risk factors and clinical profiles in Turkish children with cerebral palsy: analysis of 625 cases. Int J Rehabil Res 2008; 31 (01) 89-91
- 9 Mbonda E, Nguefack S, Chiabi A. et al Epilepsie chez les Enfants Atteints d’Infirmité Motrice Cérébrale: à Propos de 412 Observations à Yaoundé, Cameroun. Clinics in Mother and Child Health 2011; 8 (01) 1-5
- 10 Doumbia-Ouattara M, Diakité I, Tanoh KE, Broh Y, N'Cho CR, Yéo NS. . Profil épidémiologique et clinique des paralysies cérébrales à Abidjan en Côte d'Ivoire. Journal Africain 2018; 22-25
- 11 AbdElmagid D, Magdy H. Evaluation of risk factors for cerebral palsy. Egypt J Neurol Psychiat Neurosurg 2021;57(01):
- 12 Korzeniewski SJ, Slaughter J, Lenski M, Haak P, Paneth N. The complex aetiology of cerebral palsy. Nat Rev Neurol 2018; 14 (09) 528-543
- 13 Paul S, Nahar A, Bhagawati M, Kunwar AJ. A review on recent advances of cerebral palsy. Oxid Med Cell Longev 2022; 2022: 2622310
- 14 Ogunlesi T, Ogundeyi M, Adekanmbi F, Fetuga B, Ogunfowora O, Olowu A. Socio-clinical issues in cerebral palsy in Sagamu, Nigeria. SAJCH 2008; 2: 120
- 15 Zafeiriou DI, Kontopoulos EE, Tsikoulas I. Characteristics and prognosis of epilepsy in children with cerebral palsy. J Child Neurol 1999; 14 (05) 289-294
- 16 Lagunju IA, Adedokum BO, Fatunde OJ. Risk factors for epilepsy in children with cerebral palsy. AJNS 2006; 25 DOI: 10.4314/AJNS.V25I2.7585.
- 17 Aggarwal A, Mittal H, Kr Debnath S, Rai A. Neuroimaging in cerebral palsy - report from north India. Iran J Child Neurol 2013; 7 (04) 41-46
- 18 Wu YW, Croen LA, Shah SJ, Newman TB, Najjar DV. Cerebral palsy in a term population: risk factors and neuroimaging findings. Pediatrics 2006; 118 (02) 690-697