Abstract
A 32 year old woman at 22 weeks gestation underwent fetal magnetic resonance imaging
(MRI) after an ultrasound detected corpus callosum agenesis. MRI confirmed complete
agenesis and showed an enlarged left temporal lobe, moderate ventriculomegaly, and
abnormal hippocampal orientation. The fetal MRI scoring system indicated a poor prognosis.
MR tractography revealed abnormal neuronal connections. Parents were counseled and
the pregnancy was terminated due to poor prognosis. This case highlights the value
of fetal MRI and tractography in assessing agenesis of the corpus callosum and guiding
clinical decisions.
Keywords
agenesis - corpus callosum - fetal brain - fetal MRI - MR tractography
