CC BY 4.0 · Journal of Gastrointestinal and Abdominal Radiology
DOI: 10.1055/s-0044-1787963
Case Report

Hepatic Peliosis and Hemorrhage after Anabolic Steroid Abuse

Kausthubh Hegde
1   Division of Interventional Radiology, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States
,
Patrick D. Sutphin
1   Division of Interventional Radiology, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States
,
Thomas J. An
1   Division of Interventional Radiology, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States
,
Sanjeeva P. Kalva
1   Division of Interventional Radiology, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States
› Author Affiliations
Funding This research received no specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Abstract

Anabolic steroid abuse has become prevalent in modern society, with many athletes and bodybuilders using these substances for their performance-enhancing effects. A significant concern related to anabolic steroid abuse is the potential development of androgen-associated liver tumors such as hepatocellular carcinoma and adenomas. Anabolic steroid abuse has also been associated with hepatic vascular abnormalities like hepatic peliosis, a rare condition characterized by blood-filled cavities within the liver parenchyma. Hepatic peliosis can present with nonspecific symptoms or remain asymptomatic, making it difficult to diagnose without appropriate imaging studies. In this case report, the authors describe the imaging findings and management of two patients with intrahepatic bleeding associated with anabolic steroid consumption.



Publication History

Article published online:
26 June 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Petrovic A, Vukadin S, Sikora R. et al. Anabolic androgenic steroid-induced liver injury: An update. World J Gastroenterol 2022; 28 (26) 3071-3080
  • 2 Casavant MJ, Blake K, Griffith J, Yates A, Copley LM. Consequences of use of anabolic androgenic steroids. Pediatr Clin North Am 2007; 54 (04) 677-690 , x
  • 3 Fidelman N, LaBerge JM, Kerlan Jr RK. SCVIR 2002 Film Panel case 4: massive intraperitoneal hemorrhage caused by peliosis hepatis. J Vasc Interv Radiol 2002; 13 (05) 542-545
  • 4 Choi SK, Jin JS, Cho SG. et al. Spontaneous liver rupture in a patient with peliosis hepatis: a case report. World J Gastroenterol 2009; 15 (43) 5493-5497
  • 5 Hayward SR, Lucas CE, Ledgerwood AM. Recurrent spontaneous intrahepatic hemorrhage from peliosis hepatis. Arch Surg 1991; 126 (06) 782-783
  • 6 Niemi TT, Munsterhjelm E, Pöyhiä R, Hynninen MS, Salmenperä MT. The effect of N-acetylcysteine on blood coagulation and platelet function in patients undergoing open repair of abdominal aortic aneurysm. Blood Coagul Fibrinolysis 2006; 17 (01) 29-34
  • 7 Iannaccone R, Federle MP, Brancatelli G. et al. Peliosis hepatis: spectrum of imaging findings. AJR Am J Roentgenol 2006; 187 (01) W43-52