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CC BY 4.0 · Rev Bras Ortop (Sao Paulo)
DOI: 10.1055/s-0044-1786200
Artigo Original

Three-dimensional Evaluation of Gait: Kinetics, Kinematics, and Electromyographic in Patients with Mucopolysacharidosis Types IV and VI

Article in several languages: português | English
Francisco Robson Queiroz Rego 
1   Universidade Federal de Pernambuco, Recife, PE, Brasil
,
Herison Franklin Viana de Oliveira 
1   Universidade Federal de Pernambuco, Recife, PE, Brasil
,
Epitácio Leite Rolim Filho 
1   Universidade Federal de Pernambuco, Recife, PE, Brasil
› Author Affiliations Financial Support There was no financial support from public, commercial, or not-for-profit sources.
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Abstract

Objective This study evaluated and determined, through instrumented three-dimensional (3D) gait analysis, the kinetic, kinematic, and electromyographic profile of patients with mucopolysaccharidosis (MPS) IV and VI.

Methods This crossectional study included 11 patients treated at a rare diseases reference service and evaluated in a movement analysis laboratory. We collected clinical, physical examination, and kinetic, kinematic, and electromyographic data using a 3D movement system, from June 2020 to January 2021.

Results There were 5 (45.5%) female patients, and 6 (54.5%) males. Furthermore, 9 (81.8%) subjects had MPS VI, and 2 (18.2%) had MPS IV. Their average age was 14.6 years. The average speed was 0.68 m/s (±0.21), and the stride length was 0.66 (±0.15). The most altered static angles were the hips' abduction-adduction, knees' range of movement, and foot's progression angle. Most cases presented a gait pattern of hip flexion-adduction and knee flexion. The gait profile scale (GPS) was 14.58 (±6.72) on the right side and 11.71 (±3.39) on the left. The gait deviation index (GDI) was 73.23 (±14.50) on the right side and 80.45 (±17.05) on the left. Muscle activity approximately followed the current model.

Conclusion The patients showed a decreased average speed and stride length. Most cases presented a gait pattern of hip flexion-adduction and knee flexion. Both GPS and GDI showed a significant deviation from normality.

Keywords

electromyography - kinematics - kinetics - mucopolysaccharidoses - three-dimensional gait evaluation

Study developed at the Universidade Federal de Pernambuco, Hospital Maria Lucinda, and Movement Analysis Laboratory, Instituto Rolim, Recife, PE, Brazil.




Publication History

Received: 19 April 2023

Accepted: 21 July 2023

Article published online:
22 July 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)

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