CC BY-NC-ND 4.0 · Indian J Radiol Imaging
DOI: 10.1055/s-0044-1780524
Case Report

A Rare Case of Disseminated Peritoneal Leiomyomatosis: A Case Report

1   Department of Radiodiagnosis, St John's Medical College and Hospital, Bangalore, Karnataka, India
,
Twinkle T. Titus
1   Department of Radiodiagnosis, St John's Medical College and Hospital, Bangalore, Karnataka, India
,
Loana Mariyam Sebastian
1   Department of Radiodiagnosis, St John's Medical College and Hospital, Bangalore, Karnataka, India
,
Soumya Cicilet
1   Department of Radiodiagnosis, St John's Medical College and Hospital, Bangalore, Karnataka, India
› Author Affiliations

Abstract

Disseminated peritoneal leiomyomatosis is a benign condition characterized by multiple extrauterine leiomyomas in various locations such as the peritoneum, mesentery, abdominal wall, and pelvis. This is typically observed following laparoscopic myomectomy and is an extremely rare disease, with only a limited number of cases reported thus far. It primarily affects women in their reproductive age group and is believed to be associated with ovarian secretions. Leiomyomas are monoclonal smooth muscle tumors with characteristics similar to muscle on computed tomography/magnetic resonance imaging. The presence of multiple nodules dispersed throughout the peritoneal cavity may resemble malignancy. There is no conventional treatment guideline, and the approach depends on the patient's age, symptoms, fertility requirements, and previous treatment. The treatment modalities can be surgical, hormonal, or combined. The presented case involves a 40-year-old woman who developed disseminated peritoneal leiomyomatosis after undergoing laparoscopic myomectomy.



Publication History

Article published online:
23 March 2024

© 2024. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Hiremath SB, Benjamin G, Gautam AA, Panicker S, Rajan A. Disseminated peritoneal leiomyomatosis: a rare cause of enigmatic peritoneal masses. BJR Case Rep 2016; 2 (03) 20150252
  • 2 Hsieh YC, Kuo PY, Chiang YC. Leiomyomatosis peritonealis disseminata in laparoscopic port site and abdomino-pelvic cavity: a case report. Radiol Case Rep 2021; 17 (02) 293-297
  • 3 Larraín D, Rabischong B, Khoo CK, Botchorishvili R, Canis M, Mage G. “Iatrogenic” parasitic myomas: unusual late complication of laparoscopic morcellation procedures. J Minim Invasive Gynecol 2010; 17 (06) 719-724
  • 4 Willson JR, Peale AR. Multiple peritoneal leiomyomas associated with a granulosa-cell tumor of the ovary presented at a meeting of the Philadelphia Obstetrical Society, Jan. 3, 1952. Am J Obstet Gynecol 1952; 64 (01) 204-208
  • 5 Ye Z, Chen L. Leiomyomatosis peritonealis disseminata with low-grade malignant change: a case report. Medicine (Baltimore) 2022; 101 (36) e30528
  • 6 Van der Meulen JF, Pijnenborg JM, Boomsma CM, Verberg MF, Geomini PM, Bongers MY. Parasitic myoma after laparoscopic morcellation: a systematic review of the literature. BJOG 2016; 123 (01) 69-75
  • 7 Gebresellassie HW. Leiomyomatosis peritonealis disseminata in postmenopausal women: a case report with review of literature. Int Med Case Rep J 2016; 9: 309-312
  • 8 Hales HA, Peterson CM, Jones KP, Quinn JD. Leiomyomatosis peritonealis disseminata treated with a gonadotropin-releasing hormone agonist. A case report. Am J Obstet Gynecol 1992; 167 (02) 515-516
  • 9 Takeda T, Masuhara K, Kamiura S. Successful management of a leiomyomatosis peritonealis disseminata with an aromatase inhibitor. Obstet Gynecol 2008; 112 (2 Pt 2): 491-493
  • 10 Chen X, Liu H, Shi H, Fan Q, Sun D, Lang J. Leiomyomatosis peritonealis disseminata following laparoscopic surgery with uncontained morcellation: 13 cases from one institution. Front Surg 2021; 8: 788749
  • 11 Raspagliesi F, Quattrone P, Grosso G, Cobellis L, Di Re E. Malignant degeneration in leiomyomatosis peritonealis disseminata. Gynecol Oncol 1996; 61 (02) 272-274
  • 12 Quaranta M, Mehra G, Nath R, Culora G, Sayasneh A. A rare case of refractory disseminated leiomyomatosis peritonealis complicated by cauda equina compression. Eur J Obstet Gynecol Reprod Biol 2018; 229: 205-207