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CC BY 4.0 · Indian J Med Paediatr Oncol
DOI: 10.1055/s-0044-1779048
Case Report and Review of Literature

Total Splenectomy for Splenic Abscess in Pediatric Oncology: A Report of Two Cases

Ramitha R. Bhat
1   Division of Pediatric Hematology and Oncology, Manipal Comprehensive Cancer Care centre, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, India
,
Vasudeva Bhat K
1   Division of Pediatric Hematology and Oncology, Manipal Comprehensive Cancer Care centre, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, India
,
Vinay Munikoty Venkatesh
1   Division of Pediatric Hematology and Oncology, Manipal Comprehensive Cancer Care centre, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, India
,
Archana Melavarige Venkatagiri
1   Division of Pediatric Hematology and Oncology, Manipal Comprehensive Cancer Care centre, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, India
,
Shreya Joshi
1   Division of Pediatric Hematology and Oncology, Manipal Comprehensive Cancer Care centre, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, India
,
Vijay Kumar
2   Department of Pediatric Surgery, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, India
,
Santosh P Prabhu
2   Department of Pediatric Surgery, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, India
,
Vishwapriya Godkhindi 
3   Department of Pathology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, India
,
Atul Thobbi
1   Division of Pediatric Hematology and Oncology, Manipal Comprehensive Cancer Care centre, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, India
,
Chandana Pai
1   Division of Pediatric Hematology and Oncology, Manipal Comprehensive Cancer Care centre, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, India
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Abstract

Splenic abscess is a relatively uncommon condition, especially in pediatric malignancies. The diagnosis of a splenic abscess is a clinical challenge due to low incidence. The condition is fatal if not diagnosed on time. We are reporting two cases with underlying immune suppression secondary to malignancy and multidrug-resistant sepsis with splenic abscesses as the focus. Both children had life-threatening sepsis and required total splenectomy as a life-saving measure. Postsplenectomy course was uneventful with clinical improvement, and chemotherapy was continued. High suspicion is necessary due to nonspecific presentation. The treatment of splenic abscess includes conservative management and percutaneous drainage. Splenectomy is generally not indicated; however, total splenectomy may be required in the setting of multiple splenic abscesses, also to prevent overwhelming infection in an immunocompromised setting.

Keywords

splenic abscess - pediatric oncology - Klebsiella - splenectomy

Declaration by Authors

The manuscript has been read and approved by all the authors, the requirements for authorship have been met, and the manuscript represents honest work.

V.B.K. and V.M.V. conceived of the presented idea. R.R.B. and S.J. collected the case details and did the literature search. A.M.V., V.K., S.P., and V.G. contributed to the manuscript design and figures. All authors discussed the results and contributed to the final manuscript.


Declaration of the Patient Consent

The authors certify that they have obtained all appropriate patient consent forms.




Publication History

Article published online:
30 January 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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