Int J Sports Med 2018; 39(05): 397-406
DOI: 10.1055/s-0044-100387
Clinical Sciences
© Georg Thieme Verlag KG Stuttgart · New York

High-Intensity Interval Training as a Tool for Counteracting Dyslipidemia in Women

Cristian Alvarez
1   Department of Physical Activity Sciences, Universidad de Los Lagos, Osorno, Chile
Rodrigo Ramirez-Campillo
1   Department of Physical Activity Sciences, Universidad de Los Lagos, Osorno, Chile
Cristian Martinez-Salazar
2   Department of Physical Education and Recreation, Faculty of Education, Social Sciences and Humanities, Universidad de la Frontera, Temuco, Chile
Angélica Castillo
1   Department of Physical Activity Sciences, Universidad de Los Lagos, Osorno, Chile
Francisco Gallardo
1   Department of Physical Activity Sciences, Universidad de Los Lagos, Osorno, Chile
Emmanuel Gomes Ciolac
3   Exercise and Chronic Disease Research Laboratory, Physical Education Department, School of Sciences, Campus Bauru, São Paulo State University (UNESP), Bauru, Brazil
› Author Affiliations
Further Information

Publication History

accepted after revision 20 December 2017

Publication Date:
21 March 2018 (online)


Sedentary overweight or obese adult (age<60 years) women, allocated in type 2 diabetes mellitus (T2DM, n=13), dyslipidemia alone (DYS, n=12), dyslipidemia associated with hyperglycaemia (DYSHG, N=12), or healthy control (CON, n=10) groups, had their lipid, glucose, blood pressure, endurance performance, and anthropometry variables assessed before and after 16 weeks of a thrice-weekly high-intensity interval training (HIIT) program. Triglycerides reduced significantly (P<0.05) in all groups, and high-density lipoprotein increased (P<0.01) in T2DM, DYS and DYSHG; however, low-density lipoprotein reduced (P<0.05) only in DYSHG, and total cholesterol reduced (P<0.01) only in DYS and DYSHG. Fasting glucose reduced (P<0.05) significantly in T2DM, DYS and DYSHG, but with higher decreases in T2DM and DYSHG. Blood pressure, endurance performance and body composition improved (P<0.05) in all groups. The HIIT program was effective for restoring lipid profile of DYS and DYSHG, and fasting glucose of DYSHG to levels similar to those of CON, with a weekly time commitment 25% to 56% lower than the minimum recommended in current exercise guidelines. These findings suggest that HIIT may be a time-efficient intervention for counteracting dyslipidemia.

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