Current Evidence and Future Directions of Omega-3 Supplementation and Cardiovascular Disease Risk

Bambang Dwiputra; Anwar Santoso; Budhi Setianto Purwowiyoto; Basuni Radi; Bashar Adi Wahyu Pandhita; Serlie Fatrin; Ade Meidian Ambari

doi:10.1055/s-0043-1777258

International Journal of Angiology, Inhaltsverzeichnis

Int J Angiol 2024; 33(01): 001-007
DOI: 10.1055/s-0043-1777258

Review Article

Current Evidence and Future Directions of Omega-3 Supplementation and Cardiovascular Disease Risk

Bambang Dwiputra

¹Deptartment of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia - Harapan Kita National Cardiovascular Center, Jakarta, Indonesia

,

Anwar Santoso

¹Deptartment of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia - Harapan Kita National Cardiovascular Center, Jakarta, Indonesia

,

Budhi Setianto Purwowiyoto

¹Deptartment of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia - Harapan Kita National Cardiovascular Center, Jakarta, Indonesia

,

Basuni Radi

¹Deptartment of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia - Harapan Kita National Cardiovascular Center, Jakarta, Indonesia

,

Bashar Adi Wahyu Pandhita

¹Deptartment of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia - Harapan Kita National Cardiovascular Center, Jakarta, Indonesia

,

Serlie Fatrin

¹Deptartment of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia - Harapan Kita National Cardiovascular Center, Jakarta, Indonesia

,

Ade Meidian Ambari

¹Deptartment of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia - Harapan Kita National Cardiovascular Center, Jakarta, Indonesia

› Institutsangaben

Abstract

Omega-3 supplementation has a controversial role in the secondary prevention of cardiovascular diseases. Despite large clinical trials published over the years, the evidence of omega-3 in preventing cardiovascular diseases, especially coronary heart disease, is still inconclusive. However, recent clinical trials using higher dose of omega-3 or highly purified esters of omega-3 shows promising result, with reduction in cardiovascular death and incidence of cardiovascular disease. This review aims to summarize the possible mechanism of omega-3 in preventing cardiovascular disease and future directions of research regarding the benefit of omega-3 in cardiovascular disease.

Keywords

atherosclerosis - cardiovascular disease - prevention - fatty acid - omega-3 - eicosapentaenoic acid

Volltext

Referenzen

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