CC BY-NC-ND 4.0 · Asian J Neurosurg 2023; 18(04): 836-838
DOI: 10.1055/s-0043-1776736
Letter to the Editor

A Case-Based Review of Management of CNS Melioidosis

Debajyoti Datta
1   Department of Neurosurgery, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
1   Department of Neurosurgery, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
Ashis Patnaik
1   Department of Neurosurgery, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
2   Department of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
› Author Affiliations
Funding None.


India is recently witnessing a surge in cases of melioidosis, usually considered an endemic disease and an important public health problem in Southeast Asia and Northern Australia.[1] It is caused by Burkholderia pseudomallei, an environmental saprophytic gram-negative bacterium, which predominantly affects persons with diabetes mellitus and various other underlying predispositions such as heavy alcohol intake, chronic pulmonary disease, chronic renal disease, glucocorticoid therapy, and malignancy. The clinical manifestations range from a mild subacute disease with localized lesions to a fulminant septicemic form. Involvement of central nervous system (CNS) is an unusual event. We report a case of intracranial melioidosis manifested as a brain abscess in an occupationally unexposed patient, who had an excellent outcome owing to appropriate neurosurgical intervention, accurate etiological identification, and effective antibiotic therapy.

Ethical Approval and Consent to Participate

Institute ethical standards were followed. Consent to participate was taken from individual patient.

Consent for Publication

Publication consent taken from the patient and the parent.

Availability of Data and Material

All available date presented in the article.

Authors' Contributions

A.S. was involved in patient care and preparation of the final draft. D.D. helped in first draft preparation, review of literature, and patient care. A.P. and S.M. were involved in patient care.

Publication History

Article published online:
29 December 2023

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