Summary
The immunological parameters of 30 patients admitted within 6 hours of burns injury
were compared with those of controls. Serum levels of immunoglobulins (IgG, IgA, IgM),
complements (C3 & C4) and proteins (total & albumin) were estimated on admission and
two weeks later in surviving patients. The aim of this prospective study was to find
out the clinical importance of immunological monitoring in burns patients. It was
observed that the initial fall and rebound increase in C3 and C4 levels were found
to be highly significant.
We conclude that IgA, IgG, C3 and C4 monitoring can help in predicting prognosis of
burns patients. Base on the immunological parameters initially in nonsurvivors and
two weeks later in surviving patients we can say hypothetically that prophylactic
or therapeutic administration of immunoglobulins for their general or specific role
could bring hopes for burns patients in future.
