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CC BY 4.0 · Rev Bras Ortop (Sao Paulo) 2024; 59(01): e1-e9
DOI: 10.1055/s-0043-1776021
Artigo de Atualização
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Bone Regenerate Evaluation Methods[*]

Article in several languages: português | English

Authors

  • Gracielle Silva Cardoso 

    1   Serviço de Ortopedia e Traumatologia, Hospital Governador Celso Ramos, Florianópolis, SC, Brasil

  • Renato Amorim 

    1   Serviço de Ortopedia e Traumatologia, Hospital Governador Celso Ramos, Florianópolis, SC, Brasil


Financial Support The authors declare that they have not received any financial support from public, commercial, or not-for-profit sources to conduct the present study.
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Abstract

Since its introduction by Ilizarov, the distraction osteogenesis technique has been used to treat trauma-related conditions, infections, bone tumors, and congenital diseases, either as methods of bone transport or elongation. One of the major dilemmas for the orthopedic surgeon who performs osteogenic distraction is establishing a reproducible method of assessing the progression of the osteogenesis, enabling the early detection of regenerate failures, in order to effectively interfere during treatment, and to determine the appropriate time to remove the external fixator. Several quantitative monitoring methods to evaluate the structural recovery and biomechanical properties of the bone regenerate at different stages, as well as the bone healing process, are under study. These methods can reveal data on bone metabolism, stiffness, bone mineral content, and bone mineral density. The present review comprehensively summarizes the most recent techniques to assess bone healing during osteogenic distraction, including conventional radiography and pixel values in digital radiology, ultrasonography, bone densitometry and scintigraphy, quantitative computed tomography, biomechanical evaluation, biochemical markers, and mathematical models. We believe it is crucial to know the different methods currently available, and we understand that using several monitoring methods simultaneously can be an ideal solution, pointing to a future direction in the follow-up of osteogenic distraction.

Keywords

quantitative evaluation - osteogenic distraction - biomechanical phenomena - external fixation - X-ray

* Work developed at the Orthopedics and Traumatology Service, Hospital Governador Celso Ramos, Florianópolis, SC, Brazil.




Publication History

Received: 19 September 2022

Accepted: 12 April 2023

Article published online:
21 March 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)

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