A Large Mandibular Anterior Swelling—A Diagnostic Dilemma: A Case Report

Abstract

Hybrid lesions are lesions that combine characteristics of many pathologies. The literature has shown a rare relationship between aneurysmal bone cysts, fibro-osseous lesions, and a central giant cell lesion. In this case, we describe an unusual hybrid lesion in the mandibular anterior area. As a result, the goal of this article is to highlight the significance of comprehensive clinical, radiographic, and histological investigation in addition to presenting a rare instance of hybrid lesion. This will lessen the likelihood of misdiagnosis in these situations and aid in prompt treatment planning of the lesion.

Keywords

hybrid lesions - aneurysmal bone cysts - ossifying fibroma - central giant cell granuloma

Publication History

Article published online:
18 January 2024

• References

• 1 Crusoé-Rebello I, Torres MG, Burgos V. et al. Hybrid lesion: central giant cell granuloma and benign fibro-osseous lesion. Dentomaxillofac Radiol 2009; 38 (06) 421-425
• 2 Rai A, Ahmad SA, Saleem M, Faisal M. Hybrid central giant cell granuloma and central ossifying fibroma: case report and literature review. J Oral Maxillofac Surg Med Pathol 2019; 31 (04) 258-263
• 3 Pontes FSC, Mosqueda-Taylor A, de Souza LL. et al. Hybrid odontogenic lesions: a systematic review of 203 cases reported in the literature. J Oral Pathol Med 2022; 51 (01) 5-12
• 4 El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. WHO Classification of Head and Neck Tumors. 4th ed. Lyon: IARC Press; 2017
• 5 Richardson J, Litman E, Stanbouly D, Lee KC, Philipone E. Aneurysmal bone cyst of the head & neck: a review of reported cases in the literature. J Stomatol Oral Maxillofac Surg 2022; 123 (01) 59-63
• 6 Robinson PD. Aneurysmal bone cyst: a hybrid lesion?. Br J Oral Maxillofac Surg 1985; 23 (03) 220-226
• 7 López-Arcas JM, Cebrián L, González J, Burgueño M. Aneurysmal bone cyst of the mandible: case presentation and review of the literatura. Med Oral Patol Oral Cir Bucal 2007; 12: 401-403
• 8 Pelo S, Gasparini G, Boniello R, Moro A, Amoroso PF. Aneurysmal bone cyst located in the mandibular condyle. Head Face Med 2009; 5: 8
• 9 Chrcanovic BR, Gomez RS. Juvenile ossifying fibroma of the jaws and paranasal sinuses: a systematic review of the cases reported in the literature. Int J Oral Maxillofac Implants 2020; 49 (01) 28-37
• 10 Penfold CN, McCullagh P, Eveson JW, Ramsay A. Giant cell lesions complicating fibro-osseous conditions of the jaws. Int J Oral Maxillofac Surg 1993; 22 (03) 158-162
• 11 Ramesh V. “Central giant cell granuloma” - an update. J Oral Maxillofac Pathol 2020; 24 (03) 413-415
• 12 MacDonald-Jankowski D. Fibro-osseous lesions of the face and jaws. Clin Radiol 2011; 66 (01) 46-58
• 13 Waldron CA. Fibro-osseous lesions of the jaws. J Oral Maxillofac Surg 2003; 61 (06) 724-731
• 14 Fletcher CDM, Bridge JA, Hogendoorn PCW. et al, Eds. WHO Classification of Tumours of Soft Tissue and Bone. 4th ed. Lyon: IARC Press; 2013. . Chapter 7: Osteosarcoma
• 15 Bacci G, Longhi A, Versari M, Mercuri M, Briccoli A, Picci P. Prognostic factors for osteosarcoma of the extremity treated with neoadjuvant chemotherapy: 15-year experience in 789 patients treated at a single institution. Cancer 2006; 106 (05) 1154-1161
• 16 Capote-Moreno A, Acero J, García-Recuero I, Ruiz J, Serrano R, de Paz V. Giant aneurysmal bone cyst of the mandible with unusual presentation. Med Oral Patol Oral Cir Bucal 2009; 14 (03) E137-E140
• 17 Kalantar Motamedi MH. Aneurysmal bone cysts of the jaws: clinicopathological features, radiographic evaluation and treatment analysis of 17 cases. J Craniomaxillofac Surg 1998; 26 (01) 56-62
• 18 Goyal A, Tyagi I, Syal R, Agrawal T, Jain M. Primary aneurysmal bone cyst of coronoid process. BMC Ear Nose Throat Disord 2006; 6: 4
• 19 Kransdorf MJ, Sweet DE. Aneurysmal bone cyst: concept, controversy, clinical presentation, and imaging. AJR Am J Roentgenol 1995; 164 (03) 573-580
• 20 Sonone A, Hande A, Gawande MN, Patil SK, Pakhale A. Aneurysmal bone cyst plus lesions: a case report and a literature review. Cureus 2022; 14 (08) e27912
• 21 Bertrand G, Minard MF, Simard C, Rebel A. [Ultrastructural study of a case of monostotic fibrous dysplasia]. Ann Anat Pathol (Paris) 1978; 23 (01) 81-89
• 22 Karabouta I, Tsodoulos S, Trigonidis G. Extensive aneurysmal bone cyst of the mandible: surgical resection and immediate reconstruction. A case report. Oral Surg Oral Med Oral Pathol 1991; 71 (02) 148-150
• 23 Devi P, Thimmarasa V, Mehrotra V, Agarwal M. Aneurysmal bone cyst of the mandible: a case report and review of literature. J Oral Maxillofac Pathol 2011; 15 (01) 105-108