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DOI: 10.1055/s-0043-1775701
Role of Vitamin E in Ischaemic Skin Flap Survival in Rats
Summary
The efficacy of free radical scavenger – Vitamin E (VE) in salvage of ischaemic skin flaps was studied in an experimental rat skin flap model. The animals were divided into two groups – a control group (N=15) who did of receive VE and a test group (N=15) who received VE starting one week preoperatively. No significant difference was found in flap necrosis between the control group (38.365% ± 1.398% SEM) and the test group (35.288% ± 0.635% SEM), which received therapeutic dose of VE (100 mg/kg/day. 1 mg = 1.49 I.U). Further research is needed to establish the role of vitamin E as an agent of ischaemic skin flap salvage.
Publikationsverlauf
Artikel online veröffentlicht:
15. September 2023
© 2023. Association of Plastic Surgeons of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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