CC BY-NC-ND 4.0 · Asian J Neurosurg 2024; 19(01): 101-104
DOI: 10.1055/s-0043-1772760
Case Report

Brachioradial Pruritus Caused by Cervical Disc Herniation Precipitated by Trauma Treated with Anterior Cervical Discectomy and Fusion: Report of Two Cases and Review of the Literature

Nicholas S. Hernandez
Martin H. Pham
Funding None.


Brachioradial pruritis (BRP) is a rare form of dermatomal pruritis that appears to be caused both by cervical radiculopathy and exposure to ultraviolet-light, although the exact pathophysiology for the manifestation of these symptoms remains to be determined. A diagnosis of BRP is typically confirmed with the “ice-pack” test and evidence of cervical spine pathology using magnetic resonance imaging. Treatment options consist of application of ice, reduction in sun exposure, and topical capsaicin, antiepileptics, or tricyclic antidepressants. Patients with refractory symptoms and cervical spine pathology may be candidates for surgical decompression, particularly at the C5 and C6 levels. However, there are currently no established guidelines to treat BRP, or surgical procedures that have shown to be superior. Here, we report two cases of cervical disc herniations after traumatic events that presented as BRP. Both cases were successfully treated with anterior cervical discectomy and fusion with complete resolution of symptoms.

Authors' Contribution

MHP was involved in conceptualization and data acquisition. MHP and NSH helped in literature search, manuscript editing and review. NSH, MHP, and JLR prepared manuscript. MHP has provided guarantee.

Publication History

Article published online:
09 April 2024

© 2024. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

  • References

  • 1 Crevits L. Brachioradial pruritus–a peculiar neuropathic disorder. Clin Neurol Neurosurg 2006; 108 (08) 803-805
  • 2 Cohen AD, Masalha R, Medvedovsky E, Vardy DA. Brachioradial pruritus: a symptom of neuropathy. J Am Acad Dermatol 2003; 48 (06) 825-828
  • 3 Goodkin R, Wingard E, Bernhard JD. Brachioradial pruritus: cervical spine disease and neurogenic/neuropathic [corrected] pruritus. J Am Acad Dermatol 2003; 48 (04) 521-524
  • 4 Mirzoyev SA, Davis MD. Brachioradial pruritus: Mayo Clinic experience over the past decade. Br J Dermatol 2013; 169 (05) 1007-1015
  • 5 Binder A, Fölster-Holst R, Sahan G. et al. A case of neuropathic brachioradial pruritus caused by cervical disc herniation. Nat Clin Pract Neurol 2008; 4 (06) 338-342
  • 6 Carvalho S, Sanches M, Alves R, Selores M. Brachioradial pruritus in a patient with cervical disc herniation and Parsonage-Turner syndrome. An Bras Dermatol 2015; 90 (03) 401-402
  • 7 Marziniak M, Phan NQ, Raap U. et al. Brachioradial pruritus as a result of cervical spine pathology: the results of a magnetic resonance tomography study. J Am Acad Dermatol 2011; 65 (04) 756-762
  • 8 Veien NK, Laurberg G. Brachioradial pruritus: a follow-up of 76 patients. Acta Derm Venereol 2011; 91 (02) 183-185
  • 9 Poterucha TJ, Murphy SL, Davis MD. et al. Topical amitriptyline-ketamine for the treatment of brachioradial pruritus. JAMA Dermatol 2013; 149 (02) 148-150
  • 10 Yilmaz S, Ceyhan AM, Baysal Akkaya V. Brachioradial pruritus successfully treated with gabapentin. J Dermatol 2010; 37 (07) 662-665
  • 11 Lane JE, McKenzie JT, Spiegel J. Brachioradial pruritus: a case report and review of the literature. Cutis 2008; 81 (01) 37-40
  • 12 Waisman M. Solar pruritus of the elbows (brachioradial summer pruritus). Arch Dermatol 1968; 98 (05) 481-485
  • 13 De Ridder D, Hans G, Pals P, Menovsky T. A C-fiber-mediated neuropathic brachioradial pruritus. J Neurosurg 2010; 113 (01) 118-121
  • 14 Weinberg BD, Amans M, Deviren S, Berger T, Shah V. Brachioradial pruritus treated with computed tomography-guided cervical nerve root block: a case series. JAAD Case Rep 2018; 4 (07) 640-644
  • 15 Savk O, Savk E. Investigation of spinal pathology in nostalgia paresthetica. J Am Acad Dermatol 2005; 52 (06) 1085-1087
  • 16 Alai NN, Skinner HB. Concurrent nostalgia paresthetica and brachioradial pruritus associated with cervical degenerative disc disease. Cutis 2018; 102 (03) 185 , 186, 189, 190
  • 17 Kwatra SG, Stander S, Bernhard JD, Weisshaar E, Yosipovitch G. Brachioradial pruritus: a trigger for generalization of itch. J Am Acad Dermatol 2013; 68 (05) 870-873