Open Access
CC BY 4.0 · Indian J Med Paediatr Oncol 2023; 44(05): 474-481
DOI: 10.1055/s-0043-1772204
Review Article

Flow Cytometry in the Diagnostic Laboratory Workup of Acute Lymphoblastic Leukemias

1   Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
1   Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Nabhajit Mallik
1   Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
› Institutsangaben

Funding None.
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Abstract

Acute lymphoblastic leukemias (ALLs) are hematological neoplasms characterized by clonal proliferation of lymphoid blasts, which can be B- or T-cell type. Flow cytometric immunophenotyping is an integral component in establishing blast lineage during the diagnostic workup of ALLs, aiding in appropriate therapy, prognostication, and monitoring of the disease. The current review focuses on the utility of flow cytometry in the workup of ALLs, including the usefulness of various antibodies and pitfalls in diagnosis.



Publikationsverlauf

Artikel online veröffentlicht:
04. November 2023

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