Digestive Disease Interventions 2023; 07(04): 280-287
DOI: 10.1055/s-0043-1771480
Review Article

Liver Biopsy and Pressure Hemodynamics: GI Perspective

1   Department of Gastroenterology, Carilion Clinic, Roanoke, Virginia
2   Virginia Tech Carilion School of Medicine, Roanoke, Virginia
Vivek Kesar
1   Department of Gastroenterology, Carilion Clinic, Roanoke, Virginia
2   Virginia Tech Carilion School of Medicine, Roanoke, Virginia
Klaus Monkemuller
1   Department of Gastroenterology, Carilion Clinic, Roanoke, Virginia
2   Virginia Tech Carilion School of Medicine, Roanoke, Virginia
Paul Yeaton
1   Department of Gastroenterology, Carilion Clinic, Roanoke, Virginia
2   Virginia Tech Carilion School of Medicine, Roanoke, Virginia
› Author Affiliations


Endoscopic ultrasound (EUS) has come a long way from mere diagnostic modality to performing interventional procedures like fine needle aspiration, gastric varices glue and coiling, and management of pancreatic fluid collection along with necrosectomy. Recently, EUS-guided biopsy of the liver has gained traction. This coupled with the ability to access the portal vein and measure portal pressure has made comprehensive liver evaluation possible using endoscopic route. In this review, we will discuss evolution and techniques of performing EUS-guided liver biopsy and portal pressure gradient. We will also compare the merits and demerits as compared with the other conventional techniques.

Publication History

Received: 06 December 2023

Accepted: 23 June 2023

Article published online:
18 September 2023

© 2023. Thieme. All rights reserved.

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