A proportion of patients who undergo total neoadjuvant therapy for rectal cancer will
achieve what is classified as a near-complete response. Significant debate exists
as to the optimal management strategy for these patients with large heterogeneity
in management. This article will examine the therapeutic and surveillance options
for these patients as well as the relevant outcomes data.
Keywords
rectal cancer - chemoradiation - total neoadjuvant therapy - local excision - watch
and wait
