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Homœopathic Links 2023; 36(02): 147-151
DOI: 10.1055/s-0043-1769474
Case Report

Management of Generalised Anxiety Disorder through Individualised Homoeopathic Medicine: A Case Study

Azizul Islam Khadim
1   Regional Research Institute of Homoeopathy, Under Central Council for Research in Homoeopathy, Khumulwng, Agartala, Tripura, India
› Author Affiliations Funding No external source of funding was required for the study.
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Abstract

Background Anxiety disorder is the most common psychological problem in this modern era. It is characterised by cognitive, somatic, emotional and behavioural components. Anxiety can affect the quality of life of an individual and can interfere with a person's career, academics, job, family and social life. Owing to the prolonged side effects from conventional medication, patients turn towards homoeopathy for safe, gentle and effective treatment.

Method A 23-year-old male diagnosed with generalised anxiety disorder (GAD) came to outpatient department after having consulted other physicians without benefit. The patient received individualised homoeopathic medicine. Outcome was measured using the GAD-7 every 3 months.

Results At the start of the treatment, the patient's GAD-7 score was 16 which reflected severe anxiety. After 9 months, it was reduced to 2.

Conclusion This case demonstrates the utility of individualised homoeopathic treatment in improving GAD within 9 months of treatment. Nevertheless, large sample randomised controlled study would be required to support this single case observation.

Keywords

GAD - GAD-7 Score - individualised medicine - homoeopathy - Arsenicum album

Patient Consent

Written informed consent was obtained from the patient who had a free will to quit the consultation in case of any disappointment or adverse events during the course of treatment




Publication History

Article published online:
30 June 2023

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  • References

  • 1 Sartorius N. et al. The ICD-10 Classification of Mental and Behavioural Disorders Clinical Descriptions and Diagnostic Guidelines. World Health Organization; 2021: 115-116
    Google Scholar
  • 2 Diagnostic and Statistical Manual for Mental Disorders. DSM-5. 5th ed.. Washington, DC: American Psychiatric Association; 2013: 222
    Google Scholar
  • 3 Lieb R, Becker E, Altamura C. The epidemiology of generalized anxiety disorder in Europe. Eur Neuropsychopharmacol 2005; 15 (04) 445-452
    CrossrefPubMedGoogle Scholar
  • 4 Huang Y, Zhao N. Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: a web-based cross-sectional survey. Psychiatry Res 2020; 288: 112954
    CrossrefPubMedGoogle Scholar
  • 5 Machhi J, Herskovitz J, Senan AM. et al. The natural history, pathobiology, and clinical manifestations of SARS-CoV-2 infections. J Neuroimmune Pharmacol 2020; 15 (03) 359-386
    CrossrefPubMedGoogle Scholar
  • 6 Lockie AB, Kirst N, Schultz CG. Diagnosis and management of generalized anxiety disorder and panic disorder in adults. American Academy of Family Physicians 2015; Accessed May 8, 2023 at: https://www.aafp.org/pubs/afp/issues/2015/0501/p617.html
    PubMedGoogle Scholar
  • 7 Russinova Z, Wewiorski NJ, Cash D. Use of alternative health care practices by persons with serious mental illness: perceived benefits. Am J Public Health 2002; 92 (10) 1600-1603
    CrossrefPubMedGoogle Scholar
  • 8 Unützer J, Klap R, Sturm R. et al. Mental disorders and the use of alternative medicine: results from a national survey. Am J Psychiatry 2000; 157 (11) 1851-1857
    CrossrefPubMedGoogle Scholar
  • 9 Casagrande Tango R. Psychiatric side effects of medications prescribed in internal medicine. Dialogues Clin Neurosci 2003; 5 (02) 155-165
    CrossrefPubMedGoogle Scholar
  • 10 Hahnemann S. Organon of Medicine. 5th & 6th ed.. Kolkata: Modern Homoeopathic Publication; 2013: 126
    Google Scholar
  • 11 NWHRC Health centre. Anxiety Disorders: Prevention 2005 March. Accessed May 8, 2023 at: http://findarticles.com/p/articles/mi_m0PWA
    PubMedGoogle Scholar
  • 12 Lauren A, Rutter MA, Timothy AB. Psychometric properties of the generalized anxiety disorder scale- 7(GAD-7) in outpatients with anxiety and mood disorder. J Psychopathol Behav 2017; 39 (01) 140-146
    CrossrefPubMedGoogle Scholar
  • 13 Shah J. Hompath Classic. Homoeopathic Software. Version 8.0 Premium. Mumbai: Hompath; 2005
    Google Scholar
  • 14 Boericke W. Pocket Manual of Homoeopathic Materia Medica & Repertory. 9th edition.. New Delhi: B. Jain Publishers (P) Ltd; 2013: 79-83
    Google Scholar
  • 15 Allen HC. Allen's Keynote Rearranged & Classified. 10th ed.. New Delhi: B. Jain Publishers (P) Ltd.; 2013: 42-45
    Google Scholar
  • 16 Gilla D, Ahammed J, Akhila AL, Sreelakshmy SR. A review on anxiety disorders during Covid-19 pandemic homoeopathic perspective. Int J High Dilution Res. 2021; 20 (2-3): 75-85
    CrossrefPubMedGoogle Scholar
  • 17 Parewa M, Burman AS, Brahma A. et al. Individualized homoeopathic medicines in the treatment of generalized anxiety disorder: a double-blind, randomized, placebo-controlled, pilot trial. Complement Med Res 2021; 28 (05) 407-418
    CrossrefPubMedGoogle Scholar
  • 18 Gelabert RZ. Clinical study of the effectiveness of pluralist homoeopathy in generalized anxiety disorder. Altern Integr Med 2017; 6 (04) 1-6
    CrossrefPubMedGoogle Scholar
  • 19 Bonne O, Shemer Y, Gorali Y, Katz M, Shalev AY. A randomized, double-blind, placebo-controlled study of classical homeopathy in generalized anxiety disorder. J Clin Psychiatry 2003; 64 (03) 282-287
    CrossrefPubMedGoogle Scholar
  • 20 Nandini PB, Anjaneyulu K, Huban T, Vidya M, Hareesh K, Prasanna LC. Anxiolytic activity of ultra-diluted Aconitum napellus on Wistar rats. International Journal of High Dilution Research 2020; 19 (03) 40-49
    PubMedGoogle Scholar
  • 21 Coelho CDP, Motta LCSD, Arrifano V, Bernadi MM. Assessment of the effects of Zincum metallicum in maternal deprivation-induced behavioral disturbances in female rats. International Journal of High Dilution Research 2018; 17 (3-4): 42-57
    CrossrefPubMedGoogle Scholar
  • 22 Coelho CP, Chaulet VRL, Cappelli KLT, Santos RA, Vieira HC, Bernardi MM. Neurobehavioral assessment of Danio rerio intoxicated by sodium arsenate and the use of Arsenicum Album to reverse the condition of anxiety. International Journal of High Dilution Research 2018; 17 (02) 05-06
    CrossrefPubMedGoogle Scholar
  • 23 Tyagi N. An Attempt to Understand the Role of Homoeopathy in Management of Generalized Anxiety Disorder Through Clinical Case Studies. Accessed May 8, 2023 at: https://www.homeobook.com/homoeopathy-in-management-of-generalized-anxiety-disorder/
    PubMedGoogle Scholar
  • 24 Ahmad S. Homoeopathic Management of Anxiety disorders. Homeobook 30 Jan. 2012. Accessed May 8, 2023 at: https://www.homeobook.com/homoeopathic-management-of-anxiety-disorders/
    PubMedGoogle Scholar
  • 25 Niraj P, Devang P. Role of homoeopathy in Covid-19 management-a clinical experience. World J Pharm Res 2020; 9 (05) 2459-2466
    PubMedGoogle Scholar
  • 26 Lal R. et al. Pharmacological investigation on acute and sub-acute studies of Arsenicum album in experimental rats. Research square Sep 2022; Accessed May 8, 2023 at: https://www.researchsquare.com/article/re-2068666/v1.pdf
    PubMedGoogle Scholar
  • 27 Zhu LJ, Ni HU, Chen R. et al. Hippocampal nuclear factor kappa B accounts behaviors via enhancing neuronal nitric oxide synthase (Nnos)-carboxy-terminal PDZ ligand of Nnos-Dexras1 coupling. J Neurochem 2018; 146 (05) 598-612
    CrossrefPubMedGoogle Scholar
  • 28 Koo JW, Russo SJ, Ferguson D, Nestler EJ, Duman RS. Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior. Proc Natl Acad Sci U S A 2010; 107 (06) 2669-2674
    CrossrefPubMedGoogle Scholar
  • 29 Alshammari MA, Khan MR, Majid Mahmood H. et al. Systemic TNF-α blockade attenuates anxiety and depressive-like behaviors in db/db mice through downregulation of inflammatory signaling in peripheral immune cells. Saudi Pharm J 2020; 28 (05) 621-629
    CrossrefPubMedGoogle Scholar