Vet Comp Orthop Traumatol 2023; 36(06): 279-286
DOI: 10.1055/s-0043-1768991
Original Research

Post-sterilization Dimensional Accuracy of Methacrylate Monomer Biocompatible Three-Dimensionally Printed Mock Surgical Guides

Danielle M. Marturello
1   Department of Small Animal Clinical Sciences, Michigan State University, East Lansing, Michigan, United States
Loïc M. Déjardin
1   Department of Small Animal Clinical Sciences, Michigan State University, East Lansing, Michigan, United States
› Author Affiliations


Objectives The aim of this study was to evaluate the post-sterilization dimensional accuracy of a standardized drilling guide, three-dimensionally printed using biocompatible methacrylate monomers.

Study Design A mock surgical guide was designed and printed in five resins (n = 5/material) using a commercially available desktop stereolithography printer. Pre- and post-sterilization dimensions were measured for each sterilization method (steam, ethylene oxide, hydrogen peroxide gas), then statistically compared; p-value less than or equal 0.05 was considered significant.

Results While all resins produced highly accurate replicas of the designed guide, the amber and black resins were unaffected by any sterilization method (p ≥ 0.9). For other materials, ethylene oxide produced the largest dimensional changes. However, mean post-sterilization dimensional changes for all materials and sterilization methods remained less than or equal to 0.05mm

Conclusion This study demonstrated that post-sterilization dimensional change of evaluated biomaterials was minimal, and less than previously reported. Additionally, amber and black resins may be preferred to reduce post-sterilization dimensional change, as they were unaffected by any sterilization method. Given the results of this study, surgeons should feel confident using the Form 3B printer to create patient surgical guides. Furthermore, bioresins may provide safer alternatives for patients compared with other three-dimensional printed materials.

Authors' Contribution

D.M.M. contributed to the conception, study design, acquisition of data, data analysis and interpretation. L.M.D. contributed to study design. All authors drafted, revised, and approved the submitted manuscript and are publicly responsible for the relevant content.

Publication History

Received: 19 December 2022

Accepted: 22 April 2023

Article published online:
16 June 2023

© 2023. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

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