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Evaluation of Differential Sensitivity for Frequency, Intensity, and Duration in Individuals with Hypertension
Objective Hypertension is a condition in which the blood vessels have persistently raised pressure. The damage of the cochlea is due to the loss of sensitive hair cells in the inner ear or the damage to the eighth cranial nerve. When the cochlea is damaged, the functioning abilities such as coding, differentiation, and temporal processing abilities will be affected. Hence, there might be deficits in differential sensitivity in individuals with hypertension. The aim of this article was to study the effect of hypertension on differential sensitivity as there is limited literature in this area.
Method Thirty participants were included in the study and classified into two groups: group I as individuals with hypertension and group II as individuals with normal blood pressure in the age range of 25 to 45 years. Psychophysical tests like frequency, intensity, and time discrimination tests were performed using the maximum likelihood procedure (MLP) toolbox, which implements a maximum likelihood procedure for threshold estimation in MATLAB.
Results In all the three test conditions, the scores were significantly poorer in individuals with hypertension compared with individuals of the normal at all the frequencies such as 500 Hz, 1,000 Hz, 2,000 Hz, and 4,000 Hz.
Conclusion This could be because of reduced frequency selectivity and poor temporal coding as well as due to difficulty responding to rapid change in the envelope of sound over time because of cochlear and neural damage in individuals with hypertension.
Article published online:
26 May 2023
© 2023. Indian Society of Otology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
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- 1 Mackay J, Mensah GA. The Atlas of Heart Disease and Stroke. Geneva: World Health Organization; 2004
- 2 Gupta R. Trends in hypertension epidemiology in India. J Hum Hypertens 2004; 18 (02) 73-78
- 3 Srinath Reddy K, Shah B, Varghese C, Ramadoss A. Responding to the threat of chronic diseases in India. Lancet 2005; 366 (9498) 1744-1749
- 4 Lim SS, Vos T, Flaxman AD. et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380 (9859) 2224-2260
- 5 Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet 2005; 365 (9455) 217-223
- 6 Das SK, Sanyal K, Basu A. Study of urban community survey in India: growing trend of high prevalence of hypertension in a developing country. Int J Med Sci 2005; 2 (02) 70-78
- 7 World Health Organization (WHO). Noncommunicable Diseases Country Profiles, 2018. Geneva: WHO; 2018
- 8 Agarwal S, Mishra A, Jagade M, Kasbekar V, Nagle SK. Effects of hypertension on hearing. Indian J Otolaryngol Head Neck Surg 2013; 65 (Suppl. 03) 614-618
- 9 de Moraes Marchiori LL, de Almeida Rego Filho E, Matsuo T. Hypertension as a factor associated with hearing loss. Rev Bras Otorrinolaringol (Engl Ed) 2006; 72 (04) 533-540
- 10 Soares MA, Sanches SGG, Matas CG, Samelli AG. The audiological profile of adults with and without hypertension. Clinics (São Paulo) 2016; 71 (04) 187-192
- 11 Goyal G, Mittal A, Chaudhary C, Bachhel R, Grewal S, Rai M. The impact of severity of hypertension on auditory brainstem responses. Int J Med Public Health 2014; 4 (03) 218-221
- 12 Shofner WP. Representation of the spectral dominance region of pitch in the steady-state temporal discharge patterns of cochlear nucleus units. J Acoust Soc Am 2008; 124 (05) 3038-3052
- 13 Grassi M, Soranzo A. MLP: a MATLAB toolbox for rapid and reliable auditory threshold estimation. Behav Res Methods 2009; 41 (01) 20-28
- 14 Green DM. Stimulus selection in adaptive psychophysical procedures. J Acoust Soc Am 1990; 87 (06) 2662-2674
- 15 Green DM. A maximum-likelihood method for estimating thresholds in a yes-no task. J Acoust Soc Am 1993; 93 (4 Pt 1) 2096-2105
- 16 Jain C, Mohamed H, Kumar AU. Short-term musical training and pyschoacoustical abilities. Audiology Res 2014; 4 (01) 102 DOI: 10.4081/audiores.2014.102.
- 17 Giles TD, Berk BC, Black HR. et al. Expanding the definition and classification of hypertension. J Clin Hypertens (Greenwich) 2005; 7 (09) 505-512
- 18 Falkner B, Lurbe E, Schaefer F. High blood pressure in children: clinical and health policy implications. J Clin Hypertens (Greenwich) 2010; 12 (04) 261-276
- 19 Bachor E, Selig YK, Jahnke K, Rettinger G, Karmody CS. Vascular variations of the inner ear. Acta Otolaryngol 2001; 121 (01) 35-41
- 20 Nagahara K, Fisch U, Yagi N. Perilymph oxygenation in sudden and progressive sensorineural hearing loss. Acta Otolaryngol 1983; 96 (1-2) 57-68
- 21 Ohinata Y, Makimoto K, Kawakami M, Haginomori S, Araki M, Takahashi H. Blood viscosity and plasma viscosity in patients with sudden deafness. Acta Otolaryngol 1994; 114 (06) 601-607
- 22 Rarey KE, Ma YL, Gerhardt KJ, Fregly MJ, Garg LC, Rybak LP. Correlative evidence of hypertension and altered cochlear microhomeostasis: electrophysiological changes in the spontaneously hypertensive rat. Hear Res 1996; 102 (1-2) 63-69
- 23 Khullar S, Gupta N, Babbar R. Auditory brainstem responses & nerve conduction velocity in essential hypertension. Vasc Dis Prev 2009; 6 (01) 51-55 https://benthamopen.com/ABSTRACT/VDP-6-51