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CC BY 4.0 · Indian J Med Paediatr Oncol
DOI: 10.1055/s-0043-1768049
Review Article

The Effects of Dietary Nutrient Intake on Cervical Cancer: A Brief Review

Suchismita Nath
1   Department of Microbiology, Raiganj University, Raiganj, Uttar Dinajpur, West Bengal, India
,
Sultana S. Nasrin
1   Department of Microbiology, Raiganj University, Raiganj, Uttar Dinajpur, West Bengal, India
,
Amrita Samanta
1   Department of Microbiology, Raiganj University, Raiganj, Uttar Dinajpur, West Bengal, India
,
Anzum Nuzhad
1   Department of Microbiology, Raiganj University, Raiganj, Uttar Dinajpur, West Bengal, India
,
Pritha Ghosh
1   Department of Microbiology, Raiganj University, Raiganj, Uttar Dinajpur, West Bengal, India
,
Atanu Manna
1   Department of Microbiology, Raiganj University, Raiganj, Uttar Dinajpur, West Bengal, India
,
Satyasundar Pradhan
1   Department of Microbiology, Raiganj University, Raiganj, Uttar Dinajpur, West Bengal, India
,
Suresh Maity
1   Department of Microbiology, Raiganj University, Raiganj, Uttar Dinajpur, West Bengal, India
,
Srikanta Pal
1   Department of Microbiology, Raiganj University, Raiganj, Uttar Dinajpur, West Bengal, India
,
P.K. Das Mohapatra
1   Department of Microbiology, Raiganj University, Raiganj, Uttar Dinajpur, West Bengal, India
,
Subhas Chandra Jana
1   Department of Microbiology, Raiganj University, Raiganj, Uttar Dinajpur, West Bengal, India
› Author Affiliations Funding This research received funding from ICMR.
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Abstract

Cervical cancer (CC) results from a subsequent process, starting from the infection of normal cervical epithelium with oncogenic human papillomavirus and gradually progressing to cervical intraepithelial neoplasia (CIN), before finally developing into invasive cervical cancer (ICC). Over recent decades, dietary micronutrients have gained much attention due to their pivotal role in cancer prevention. We reviewed several relevant literature studies to investigate the protective roles of dietary nutrient intake in CC. Dietary intake of vitamin C, green–yellow vegetables, and provitamin A carotenoids that are rich sources of antioxidants may widely inhibit the process of CC development, whereas vitamins A and D might be more helpful in preventing the early events in the disease development. Vitamin E, lycopene, and folate are more effective for the treatment of high-grade CIN. Fruits exert their protective effects in the late stages of the cancer process, thus playing a vital role in ICC prevention. Polyphenols, flavonoids, and polyunsaturated fatty acids are more often used in cases of CC in combination with chemotherapy and radiotherapy. Thus, as a primary prevention strategy, the health benefits of various nutrients in CC must be clarified by vitro and in vivo approaches rather than epidemiological studies.

Keywords

diet - nutrition - HPV - cervical dysplasia - cervical cancer

Contributions

All the authors contributed in literature survey, collection of data, and manuscript writing.




Publication History

Article published online:
24 April 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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