CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2023; 33(03): 420-423
DOI: 10.1055/s-0043-1767694
Case Report

An Atypical Presentation of Hepatocellular Carcinoma with Multisite Metastasis following a Curative Liver Transplant

Patrick Gidley
1   Department of Radiology, Loyola University Medical Center, Maywood, Illinois, United States
2   Loyola University Chicago- Stritch School of Medicine, Maywood, Illinois, United States
3   Department of Pathology, Loyola University Medical Center, Maywood, Illinois, United States
4   Department of Radiology, Northwestern University- Feinberg School of Medicine, Chicago, Illinois, United States
› Author Affiliations


Hepatocellular carcinoma (HCC) is the most common primary liver malignancy, and liver transplantation is usually curative. HCC recurrences are rare after curative treatment options, although they are prevalent depending on various risk factors. We present a 71-year-old female patient with an unusual pattern of disease progression following a curative liver transplant with a metastatic presentation in the absence of alpha-fetoprotein elevation after 3 years of disease-free clinical presentation. We present this case to emphasize the importance of intermittent cross-sectional imaging in addition to ultrasound screening in HCC surveillance.


Support was provided in the form of imaging equipment. The patient described in the manuscript was from the Department of Radiology, Loyola University Medical Center, Maywood, Illinois, United States. The pathology examination was from the Department of Pathology, Loyola University Medical Center, Maywood, Illinois, United States.

Author Contributions

The manuscript has been read and approved by all the authors, and the requirements for authorship, as stated above, have been met by all the authors. This manuscript represents honest work by all the authors.

Publication History

Article published online:
10 April 2023

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