Comparison of the Clinical Outcomes of Endovascular Angioplasty for Critical Lower Limb Ischemia

Introduction: To compare the clinical outcomes of endovascular angioplasty for critical lower limb ischemia (CLI) in patients with multiple concomitant comorbidities including ESRD and DM. To identify the differences in clinical outcomes following different interventional approaches (supra and infrapopliteal).

Method(s): A total of 120 patients who had lower limb endovascular angioplasty for CLI were reviewed from database of our institution, for the period from 2017 to 2019. The patient's demographics and most relevant the clinical characteristics were studied. SPSS software was used to determine the statistical significance. Healing, minor amputation (below ankle), symptomatic relief were considered favorable outcomes while death or major above ankle amputation were considered poor outcomes within 2 years of intervention.

Result(s): Significant better outcome was found in patients who had combined versus singular approaches, in terms of radiological reflow and symptoms relief (p < 0.05). A significant correlation between disease comorbidity (i.e., number of vascular stenoses and ESRD) and the clinical outcomes (p < 0.05).

Conclusion(s): Our study implies that endovascular angioplasty with combined approach shows better reperfusion rather than the singular approach. However, the comorbid conditions significantly affect the outcomes.

Publication History

Article published online:
09 February 2023