Homeopathy 2024; 113(01): 032-040
DOI: 10.1055/s-0043-1762591
Original Research Article

Individualized Homeopathic Medicines in the Management of Symptomatic Adenotonsillar Hypertrophy in Children: A Prospective Observational Study

Hima Bindu Ponnam
1   Department of Clinical Research, Regional Research Institute for Homoeopathy, Hyderabad, Telangana, India
2   Department of Clinical Research, Central Council for Research In Homoeopathy, New Delhi, India
Ratan Chandra Shil
3   Department of Clinical Research, Regional Research Institute for Homoeopathy, Agartala, India
Vinitha E. R.
4   Department of Clinical Research, National Homoeopathy Research Institute for Mental Health, Kottayam, Kerala, India
Meetu Goel
5   Department of Clinical Research, Dr. D P Rastogi Central Research Institute for Homoeopathy, New Delhi, India
Sunil Ramteke
5   Department of Clinical Research, Dr. D P Rastogi Central Research Institute for Homoeopathy, New Delhi, India
D. Karthikeyan
6   Department of Clinical Research, Homoeopathy Research Institute for Disabilities, Chennai, Tamil Nadu, India
D. D. Arya
5   Department of Clinical Research, Dr. D P Rastogi Central Research Institute for Homoeopathy, New Delhi, India
Trupti Laxmi Swain
3   Department of Clinical Research, Regional Research Institute for Homoeopathy, Agartala, India
Navita Bagdi
2   Department of Clinical Research, Central Council for Research In Homoeopathy, New Delhi, India
Priyanka Srivastava
2   Department of Clinical Research, Central Council for Research In Homoeopathy, New Delhi, India
R. K. Manchanda
7   Department of Clinical Research, Directorate of AYUSH, NCT Delhi, India
Praveen Oberai
2   Department of Clinical Research, Central Council for Research In Homoeopathy, New Delhi, India
› Author Affiliations
Funding This study was funded by the Central Council for Research in Homoeopathy, New Delhi, India.


Background Globally, adenotonsillar hypertrophy (ATH) is one of the most prevalent upper respiratory tract disorders of children, with associated troublesome symptoms such as sleep apnea and cognitive disturbances. In this study, we evaluated the potential role of individualized homeopathic medicines in the management of symptomatic ATH in children.

Methods A multicenter prospective observational study was conducted at five institutes under the Central Council for Research in Homoeopathy, India. Primary and secondary outcomes (symptom score for adenoids, other symptoms of ATH, Mallampati score, tonsillar size, Sleep-Related Breathing Disorder of the Paediatric Sleep Questionnaire [SRBD-PSQ]) were assessed through standardized questionnaires at baseline and at 3, 6, 9 and 12 months. Radiological investigations for assessing the adenoid/nasopharyngeal (A/N) ratio were carried out at baseline, 6 and 12 months. All analyses were carried out using an intention-to-treat approach.

Results A total of 340 children were screened and 202 children suffering from ATH were enrolled and followed up monthly for 12 months. Each patient received individualized homeopathic treatment based on the totality of symptoms. Statistically significant reductions in adenoid symptom score, Mallampati score (including tonsillar size), SRBD-PSQ sleep quality assessment and A/N ratio were found over time up to 12 months (p < 0.001). Homeopathic medicines frequently indicated were Calcarea carbonicum, Phosphorus, Silicea, Sulphur, Calcarea phosphoricum, Pulsatilla, Lycopodium and Tuberculinum. No serious adverse events were recorded during the study period.

Conclusion This study suggests that homeopathic medicines may play a beneficial role in the management of symptomatic ATH in children. Well-designed comparative trials are warranted.

Authors' Contributions

R.V., P.O., R.K.M. and P.S. developed the concept and drafted the protocol. H.B.P, R.C.S., V.E.R., M.G., S.R., D.K., D.D.A, T.L.S. and N.B. were responsible for data acquisition. R.V. and H.B.P. were responsible for data analysis and evaluation. R.V. and H.B.P. were responsible for drafting the first and the edited versions of the manuscript. All authors approved the final manuscript for submission.

Supplementary Material

Publication History

Received: 09 June 2022

Accepted: 05 January 2023

Article published online:
04 April 2023

© 2023. Faculty of Homeopathy. This article is published by Thieme.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

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